ID H2B176_KAZAF Unreviewed; 1088 AA.
AC H2B176;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 13-SEP-2023, entry version 34.
DE RecName: Full=WAC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=KAFR0K00210 {ECO:0000313|EMBL:CCF60376.1};
GN ORFNames=KAFR_0K00210 {ECO:0000313|EMBL:CCF60376.1};
OS Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT
OS 1963 / NBRC 1671 / NRRL Y-8276) (Yeast) (Kluyveromyces africanus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1071382 {ECO:0000313|EMBL:CCF60376.1, ECO:0000313|Proteomes:UP000005220};
RN [1] {ECO:0000313|EMBL:CCF60376.1, ECO:0000313|Proteomes:UP000005220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 /
RC NRRL Y-8276 {ECO:0000313|Proteomes:UP000005220};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00475}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HE650831; CCF60376.1; -; Genomic_DNA.
DR RefSeq; XP_003959511.1; XM_003959462.1.
DR AlphaFoldDB; H2B176; -.
DR STRING; 1071382.H2B176; -.
DR GeneID; 13886565; -.
DR KEGG; kaf:KAFR_0K00210; -.
DR eggNOG; KOG1245; Eukaryota.
DR HOGENOM; CLU_265647_0_0_1; -.
DR InParanoid; H2B176; -.
DR OrthoDB; 1382023at2759; -.
DR Proteomes; UP000005220; Chromosome 11.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR013136; WSTF_Acf1_Cbp146.
DR PANTHER; PTHR32075; ISWI CHROMATIN-REMODELING COMPLEX SUBUNIT YPL216W-RELATED; 1.
DR PANTHER; PTHR32075:SF6; ISWI CHROMATIN-REMODELING COMPLEX SUBUNIT YPL216W-RELATED; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF10537; WAC_Acf1_DNA_bd; 1.
DR SMART; SM00571; DDT; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS51136; WAC; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00475}; Reference proteome {ECO:0000313|Proteomes:UP000005220}.
FT DOMAIN 23..130
FT /note="WAC"
FT /evidence="ECO:0000259|PROSITE:PS51136"
FT DOMAIN 368..428
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
SQ SEQUENCE 1088 AA; 124124 MW; 707F12420C44B610 CRC64;
MILYKNQVFE PPVPQTLPPN LNVPVWTIPQ TGEWFMSFAE YLKRMSFYQE RSFSCEFSNS
KHYTYFTALA IESEERNCFE KALPLTLRIA IAKKLLSQNV STLDSFIKDT LKETKKEFYL
GEKVKVISRK AEVSKINPEN TYKIIGKMKF DEIIDPETRE IIIPNYFKYR IVDDKPSFLK
ETLIVDHTQI ERDGIDLSFS ILKRFISMIL NNGQALQNQV CSIKSKYILE YGLNKRNYGV
MEEDSANRSS SDFMQEIVNR KIESTGIDGP NSILKNDAPH NDYPILNEAT STSSNATNIE
SIRTRIRDLI ETGQNEAQNN RGASCFVNQM DDLHIPFTVS SHVVSQLHRL DSNLDLVPIK
SNDKFRPSKT TGRLLEIHQF IFTFHSVLKV SQFSFEQLIA SLKCTDPQQL AGEAVKVYPA
EQLSSKGDGN EKLSTWEGNY TIRSLIESKA QNDLALKYKI IFKSFSKNDI IEEMESSGAH
LVFDIFKSLL SMLVDKEGYW GCPEIEKWTE DRGKNESSEI VEKLSSIPNF QKDNWVERLF
ERHFQNGYWV VILVGLMKDI VHVNKYKTII QSFIQNTTNW EIIPISLGPY TYRSFCSNLT
LEQKVDILWV LVDIVSTYST DVRAAIDVSE SIFRGLESES MKVTKSITLG TSAANELETS
LKHFRETQNY DIKVADTYKA HLIEIVGKLE KLERYRDFLG SKLSNQSSAR ALPVGFDKYG
NSCYFFTSEI NRVLSLSTLP VKMERPYHHG GLWLRGPRED DALLRLGISK SQLSSWKEIA
LKEGKIAATK QVFKVFQKNN RFYKIEGDKE VELMNENGVV NGSLTSIQMK IIEETPQNLL
LSDEEWLFFN KYDAVQNFLM SLEKGGHREY ILISNLMLFM PRIKRSFTVK EPLYGTDYLD
STEIMYWKDL DDLGHTNDKD ACVNGLSCEF QKSKDQSQNL EIAASRLTNL YDSTSSKKLL
ATIKKISEAT SQPYKDSLVS PSDMSVLVDT RGEDASASST FEKNLGAQAN ILTALLNHRP
LKNRNFVRAW RNRYPSMSDD PSTDEIDVNI ELEKVLQGIR SEFTGAASTV SVLEVQPTSS
QSLSGASS
//
