ID H2C724_9CREN Unreviewed; 572 AA.
AC H2C724;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=glycine--tRNA ligase {ECO:0000256|ARBA:ARBA00012829};
DE EC=6.1.1.14 {ECO:0000256|ARBA:ARBA00012829};
GN ORFNames=MetMK1DRAFT_00023710 {ECO:0000313|EMBL:EHP69601.1};
OS Metallosphaera yellowstonensis MK1.
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Metallosphaera.
OX NCBI_TaxID=671065 {ECO:0000313|EMBL:EHP69601.1, ECO:0000313|Proteomes:UP000003980};
RN [1] {ECO:0000313|EMBL:EHP69601.1, ECO:0000313|Proteomes:UP000003980}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MK1 {ECO:0000313|EMBL:EHP69601.1,
RC ECO:0000313|Proteomes:UP000003980};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Cheng J.-F., Goodwin L., Pitluck S., Peters L.,
RA Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Kozubal M., Macur R.E., Jay Z., Inskeep W., Woyke T.;
RT "Improved High-Quality Draft sequence of Metallosphaera yellowstonensis
RT MK1.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH597768; EHP69601.1; -; Genomic_DNA.
DR RefSeq; WP_009073820.1; NZ_JH597768.1.
DR AlphaFoldDB; H2C724; -.
DR STRING; 671065.MetMK1DRAFT_00023710; -.
DR eggNOG; arCOG00405; Archaea.
DR HOGENOM; CLU_015515_2_1_2; -.
DR OrthoDB; 6113at2157; -.
DR Proteomes; UP000003980; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:InterPro.
DR Gene3D; 3.30.40.230; -; 1.
DR Gene3D; 3.40.50.800; Anticodon-binding domain; 1.
DR InterPro; IPR002314; aa-tRNA-synt_IIb.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004154; Anticodon-bd.
DR InterPro; IPR036621; Anticodon-bd_dom_sf.
DR InterPro; IPR027031; Gly-tRNA_synthase/POLG2.
DR InterPro; IPR002315; tRNA-synt_gly.
DR NCBIfam; TIGR00389; glyS_dimeric; 1.
DR PANTHER; PTHR10745:SF0; GLYCINE--TRNA LIGASE; 1.
DR PANTHER; PTHR10745; GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2; 1.
DR Pfam; PF03129; HGTP_anticodon; 1.
DR Pfam; PF00587; tRNA-synt_2b; 1.
DR PRINTS; PR01043; TRNASYNTHGLY.
DR SUPFAM; SSF52954; Class II aaRS ABD-related; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 4: Predicted;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000313|EMBL:EHP69601.1}; ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000003980}.
FT DOMAIN 5..465
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 572 AA; 65801 MW; E7BE439DA56F5257 CRC64;
MPETEKVIEL AKRRGIFWPS YEIYGGVAGL YDIGPVGARI KNKIVQLWRK IFVEENSDFV
VEIETPMITP SKVLEASGHV ENFTDPIVEC QKCHKIYRAD HLIEETLRLS VEGLKPSELT
NIILQKGLKC PSCGGELGEV RNFNLLFSTT IGPYAGYVGY LRPETAQGMF TAFRRVFEST
RERLPLGIAQ VGRVGRNEIS PRQGLVRMRE FTIMEVEFFI DPEDKDVPQL ERYWEEGFHV
LFKDAKEKGG DPVRVKVKDL VSEKLVVNPW MAFWMATASR FVKSLGISEG SFYFEEKLPH
ERAHYSSQTF DQIVKVMGEK VEISGHAYRG DYDLSRHSRF SGEDLSVFKK FDKARVIKKR
SVILNRDRLR QEDKDFQREL MKLISDKKPE EVEIMIKAGG ELMGRKLSDF LSVIEREEKE
HGIRFIPHVV EPSFGVERCL YLSVLNAYRE KKDRVVLSLP KEIVPYHVAV FPLLEKDELK
ERSRKIAGEL KQKFEVLYDE SGSIGKRYAR VDEIGVPYAI TVDPQTLNDG TVTIRDRDSW
EQIRVNEGEV LQVLEKLFSG ADFNMILGEA KR
//
