ID H2CAG0_9LEPT Unreviewed; 404 AA.
AC H2CAG0;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=6-phosphofructokinase {ECO:0000313|EMBL:EHQ07327.1};
DE EC=2.7.1.11 {ECO:0000313|EMBL:EHQ07327.1};
GN ORFNames=Lepil_2654 {ECO:0000313|EMBL:EHQ07327.1};
OS Leptonema illini DSM 21528.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptonema.
OX NCBI_TaxID=929563 {ECO:0000313|EMBL:EHQ07327.1, ECO:0000313|Proteomes:UP000005737};
RN [1] {ECO:0000313|EMBL:EHQ07327.1, ECO:0000313|Proteomes:UP000005737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21528 {ECO:0000313|EMBL:EHQ07327.1,
RC ECO:0000313|Proteomes:UP000005737};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Held B.,
RA Kyrpides N., Mavromatis K., Ivanova N., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E.-M.,
RA Klenk H.-P., Eisen J.A.;
RT "The Improved High-Quality Draft genome of Leptonema illini DSM 21528.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 3/4.
CC {ECO:0000256|ARBA:ARBA00004679}.
CC -!- SIMILARITY: Belongs to the phosphofructokinase type A (PFKA) family.
CC {ECO:0000256|ARBA:ARBA00038478}.
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DR EMBL; JH597773; EHQ07327.1; -; Genomic_DNA.
DR AlphaFoldDB; H2CAG0; -.
DR STRING; 183.GCA_002009735_02038; -.
DR HOGENOM; CLU_020655_0_0_12; -.
DR UniPathway; UPA00109; UER00182.
DR Proteomes; UP000005737; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003872; F:6-phosphofructokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006002; P:fructose 6-phosphate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.450; -; 1.
DR Gene3D; 3.40.50.460; Phosphofructokinase domain; 1.
DR InterPro; IPR022953; ATP_PFK.
DR InterPro; IPR000023; Phosphofructokinase_dom.
DR InterPro; IPR035966; PKF_sf.
DR PANTHER; PTHR13697:SF52; ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE 3; 1.
DR PANTHER; PTHR13697; PHOSPHOFRUCTOKINASE; 1.
DR Pfam; PF00365; PFK; 1.
DR PRINTS; PR00476; PHFRCTKINASE.
DR SUPFAM; SSF53784; Phosphofructokinase; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EHQ07327.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EHQ07327.1}.
FT DOMAIN 5..334
FT /note="Phosphofructokinase"
FT /evidence="ECO:0000259|Pfam:PF00365"
SQ SEQUENCE 404 AA; 44166 MW; 109FA3C80253E3FD CRC64;
MAIKNIGIIT SGGDCGGLNA VIRGIALTAQ NRGLKSFIIP NGYAGLYNLV TFDRITELTQ
DRIEQIDICA AGSEAGNSRV KVSKIQDEHK YERIRDGLKK FNIDALLIAG GDDTGSVVAD
LSEQGIKCIH IPKTMDLDLM TYSVGGDSTI QRIAEFARDL RTTGRTHNRV IVMEVFGRYA
GHTAFRGGVA AGADAVLVPE IPVDFDFLYK FVRDRLFDRI GKSDVHAGTV MIVVAEGLRD
ASGNELVDPN APLDSFGHKK LMGAGRYVVK QIEDRIKKDP EIREFMKRTG QFVDGVYEIP
EVRELRPGHL VRCGFTTPVD ACFGLEVGAG AVHLALEGTF GVTVAGSRNG MVQYMDIKDA
IQQRFIDEGD VKVYESLGLC FGRPMDAHVA MKGEKISGRP HRPY
//
