ID H2CAJ7_9LEPT Unreviewed; 379 AA.
AC H2CAJ7;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHQ08375.1};
GN ORFNames=Lepil_3720 {ECO:0000313|EMBL:EHQ08375.1};
OS Leptonema illini DSM 21528.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptonema.
OX NCBI_TaxID=929563 {ECO:0000313|EMBL:EHQ08375.1, ECO:0000313|Proteomes:UP000005737};
RN [1] {ECO:0000313|EMBL:EHQ08375.1, ECO:0000313|Proteomes:UP000005737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21528 {ECO:0000313|EMBL:EHQ08375.1,
RC ECO:0000313|Proteomes:UP000005737};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Held B.,
RA Kyrpides N., Mavromatis K., Ivanova N., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E.-M.,
RA Klenk H.-P., Eisen J.A.;
RT "The Improved High-Quality Draft genome of Leptonema illini DSM 21528.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RlmI family.
CC {ECO:0000256|ARBA:ARBA00038091}.
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DR EMBL; JH597773; EHQ08375.1; -; Genomic_DNA.
DR RefSeq; WP_002775013.1; NZ_JH597773.1.
DR AlphaFoldDB; H2CAJ7; -.
DR STRING; 183.GCA_002009735_02679; -.
DR HOGENOM; CLU_014042_0_0_12; -.
DR Proteomes; UP000005737; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd21153; PUA_RlmI; 1.
DR CDD; cd11572; RlmI_M_like; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR Gene3D; 3.30.750.80; RNA methyltransferase domain (HRMD) like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR041532; RlmI-like_PUA.
DR InterPro; IPR019614; SAM-dep_methyl-trfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR42873:SF1; METHYLTRANS_SAM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42873; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE; 1.
DR Pfam; PF10672; Methyltrans_SAM; 1.
DR Pfam; PF17785; PUA_3; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000005737};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 5..66
FT /note="RlmI-like PUA"
FT /evidence="ECO:0000259|Pfam:PF17785"
FT DOMAIN 150..332
FT /note="S-adenosylmethionine-dependent methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF10672"
SQ SEQUENCE 379 AA; 41920 MW; E7C00BB54D979ADE CRC64;
MAALVLKKDR ERSVLHRHPW IFSGGVHRVD AVPAGSIVTV QSHDGAVLGA GFYDPAHQIR
CRLFHFGPLP ASGFDEAYWT ERLEKALLLR RALLPEKTTG FRLIHSESDG FPGLICDIYD
RAAVLQIQHE GARNLLQIAA SFLKARLTIH TLRVDDAWHV DGGEPVKLVE FVERGLRFKA
DLEGGQKTGF FLDQRENRRV VEERVAGRTV LNAFAYTGGF SAAALRGGAK SVLSVDLSDP
ALLLCEENVR LNAADAKHET LKADCFDYLR EIEGGRFDAI ILDPPAFAKT RSAVDRAARG
YKDINLQAMK KIAPGGLLFT FSCSQHISTD LFRKILFAAA TDAGRDVKIV DFLTQAPDHP
ISIYHPEGEY LKGCTLFVE
//
