ID   H2CCA8_9LEPT            Unreviewed;      1444 AA.
AC   H2CCA8;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=DEAD/DEAH box helicase domain protein {ECO:0000313|EMBL:EHQ06365.1};
GN   ORFNames=Lepil_1681 {ECO:0000313|EMBL:EHQ06365.1};
OS   Leptonema illini DSM 21528.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptonema.
OX   NCBI_TaxID=929563 {ECO:0000313|EMBL:EHQ06365.1, ECO:0000313|Proteomes:UP000005737};
RN   [1] {ECO:0000313|EMBL:EHQ06365.1, ECO:0000313|Proteomes:UP000005737}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21528 {ECO:0000313|EMBL:EHQ06365.1,
RC   ECO:0000313|Proteomes:UP000005737};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Held B.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E.-M.,
RA   Klenk H.-P., Eisen J.A.;
RT   "The Improved High-Quality Draft genome of Leptonema illini DSM 21528.";
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; JH597773; EHQ06365.1; -; Genomic_DNA.
DR   RefSeq; WP_002771828.1; NZ_JH597773.1.
DR   STRING; 183.GCA_002009735_02563; -.
DR   HOGENOM; CLU_002025_3_1_12; -.
DR   Proteomes; UP000005737; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR013701; DEAD/DEAH_assoc.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47962:SF5; ATP-DEPENDENT HELICASE LHR-RELATED; 1.
DR   PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08494; DEAD_assoc; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:EHQ06365.1};
KW   Hydrolase {ECO:0000313|EMBL:EHQ06365.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005737}.
FT   DOMAIN          30..220
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          261..427
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   1444 AA;  161730 MW;  8D25B65D7ED8E52D CRC64;
     MGGAAGFHPL LREYFARRFG SPTEIQEMVW PVASSGRHLL ALAPTGSGKT LAAFYSFIND
     FVTERLASGT TRLLYVSPLK ALNNDIRRNL LLPLEELHSE FENAGLAMPE IRVVTRSGDT
     PQSERNRMRR HPPEILITTP ESLNLLLASG TAGLMLNGLR AVIVDEIHAI APGLRGAHLM
     TAIERLEELA GPLQRIGLSA TVADPDRIAQ YLGGWQGEER RPVQLLYEKS PARAELDIKV
     IWNPAADGPL DTPAETVWDA LGAEIYAKIK AGTRILCFTE SRRVVERVAA LVNDLHQKQA
     EEGMTVEPVA FAHHGSLSRE IRLAVEEAFK AGRLRCVVAT SSLELGIDIG ELDEVLLLQC
     PSSVASAMQR LGRAGHRPGE VSRGTLYPLH SMDLVNGVVL RRLVDQRRLE PIRPPSSPLD
     LLAQVLISMA CEAEAAGHSL NIERAFELLR RSDTYHKLDR RHFDLTLEML QGRFQGLPFS
     GLRASLNAAG SDSLLPAPGA RLQLYQSGGT IPERGLYKLR LSGGERTLLG ELDEEFVWER
     RAGDRFVLGS RLWQIQSIGD SEVEVIPATT GWGMSPFWRA DSRDRENGFA DAVADQLDLW
     NQEMQRPGFL DRLRSEEGDD VARELLLFLQ RQREASHADL PGRYRIVAEV LPGEDDSYPV
     FLHTFWGGRR NRPFALALAA QLEGRYQTRI PYYASDDGVI VVLPAPPESE DVFSLPPELL
     DVHLEKALPE SGLFGGQFRQ SASTALLLPR KGFGRRTPLW LLRAAAGRLL EALSGKGEFP
     VTVEVYRALL RDRFDIDGLR ERLDQWQTGQ IEFVMRYVDQ PTPFAAGIDF QRVNELTYEP
     DRVGGAGHRS SYFQELLGNR WIPVSRDSVK LFEMRSLRLQ AGYAPDSEAA LSSWLEERSF
     IPQSEWQSLR DVVSQSKAAV ILSEAARNAS DASAAGSGDS AVAEAYRFAG ARESFVCYQG
     VSEILDRTSA GEGRDVPGAG DLLLRFLDWY GPVTLDRIRD LFGDLTERML EEIDEQLIRA
     PLIKDDAADC LCLRRNLERI YRLQRHHTRL APPLRPLRFL ALLVAHRQNV SVVFRKPPAQ
     VEFLQQTMER LFGSTAPISL WEQQIFPARI EGYTTASLDA LFTDSSLCFT GTGGESVFFF
     LEDEASLFLK QNDLNEKQRL QITAHSGGQS LFRAEASQRE ALLQALQEGL VAGRSISVLR
     KVARTSFRDS EEQRPQRRRW QSQADTWSVP GRAFDTDPLV VEEQSRLRVR LLLDRYGIIF
     RELLQKELPA LRWSSVFRTL CRMELAGEVH AGAFFEGLTG LQFLSAEAYK WMQGLEAFLE
     RRHVWWLNAC DPASLCGLGL MVDEERPLPS RLPGNRMIYR GEKLAAVLTR QGRVIQFFDA
     PDEIDDLKQA LLALLYVDFE PAARLTVEII NEQPSLQSPY RSALEAMGFQ SDGKALVCHR
     ERSF
//