ID H2CJC7_9LEPT Unreviewed; 355 AA.
AC H2CJC7;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Farnesyl-diphosphate synthase {ECO:0000313|EMBL:EHQ06067.1};
DE EC=2.5.1.10 {ECO:0000313|EMBL:EHQ06067.1};
GN ORFNames=Lepil_1377 {ECO:0000313|EMBL:EHQ06067.1};
OS Leptonema illini DSM 21528.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptonema.
OX NCBI_TaxID=929563 {ECO:0000313|EMBL:EHQ06067.1, ECO:0000313|Proteomes:UP000005737};
RN [1] {ECO:0000313|EMBL:EHQ06067.1, ECO:0000313|Proteomes:UP000005737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21528 {ECO:0000313|EMBL:EHQ06067.1,
RC ECO:0000313|Proteomes:UP000005737};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Held B.,
RA Kyrpides N., Mavromatis K., Ivanova N., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E.-M.,
RA Klenk H.-P., Eisen J.A.;
RT "The Improved High-Quality Draft genome of Leptonema illini DSM 21528.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; JH597773; EHQ06067.1; -; Genomic_DNA.
DR RefSeq; WP_002771255.1; NZ_JH597773.1.
DR AlphaFoldDB; H2CJC7; -.
DR STRING; 183.GCA_002009735_03915; -.
DR HOGENOM; CLU_014015_0_1_12; -.
DR Proteomes; UP000005737; Unassembled WGS sequence.
DR GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR43281; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR43281:SF1; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 2.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000005737};
KW Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:EHQ06067.1}.
SQ SEQUENCE 355 AA; 37915 MW; 7B560CFB95EB8A0E CRC64;
MTGKAGLPPR EQSLFSELGK AFETFFLSHV SDILNRESVP ELAAPSLYSL KGGGKRVRPA
LVLLCADQTE TAHPDATPKG REALITAAAI ECIHTYSLIH DDLPAMDDDD MRRGMPSCHR
RYPEWAAVLA GDTLNTFAFR LLADAGGDIA AKLRILADAA GHAGMAAGQA LDLSREKANF
PAGEGSLRFG QPHFDGPRSV PPEFGKTRLI TSDFQKAMLD LFEPVSSLEA GRQLLAIHMQ
KTGALIRASC ELGGICNQKE SHAFSAFGVG IGLLFQITDD ILDVTGDTDR LGKTAGKDER
TGKLTFPSLI GLDRSQALAH SLAAQTSGEA ASLPVSQAAR DALVNLVSYI LNRDH
//
