ID H2FTH3_OCESG Unreviewed; 451 AA.
AC H2FTH3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Sodium:proton antiporter {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=GU3_13890 {ECO:0000313|EMBL:AEY02531.1};
OS Oceanimonas sp. (strain GK1 / IBRC-M 10197).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Oceanimonas.
OX NCBI_TaxID=511062 {ECO:0000313|EMBL:AEY02531.1, ECO:0000313|Proteomes:UP000007742};
RN [1] {ECO:0000313|EMBL:AEY02531.1, ECO:0000313|Proteomes:UP000007742}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GK1 {ECO:0000313|EMBL:AEY02531.1,
RC ECO:0000313|Proteomes:UP000007742};
RX PubMed=22461556; DOI=10.1128/JB.00023-12;
RA Parsa Yeganeh L., Azarbaijani R., Sarikhan S., Mousavi H., Ramezani M.,
RA Amoozegar M.A., Shahzadeh Fazeli A., Salekdeh G.H.;
RT "Complete genome sequence of Oceanimonas sp. GK1, a halotolerant bacterium
RT from Gavkhouni Wetland in Iran.";
RL J. Bacteriol. 194:2123-2124(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP003171; AEY02531.1; -; Genomic_DNA.
DR RefSeq; WP_014293238.1; NC_016745.1.
DR AlphaFoldDB; H2FTH3; -.
DR STRING; 511062.GU3_13890; -.
DR KEGG; oce:GU3_13890; -.
DR eggNOG; COG2056; Bacteria.
DR HOGENOM; CLU_037927_0_0_6; -.
DR OrthoDB; 9772446at2; -.
DR Proteomes; UP000007742; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR InterPro; IPR032813; Na_H_antiport_N.
DR PANTHER; PTHR37821; AMINO ACID TRANSPORTER YUIF-RELATED; 1.
DR PANTHER; PTHR37821:SF1; AMINO ACID TRANSPORTER YUIF-RELATED; 1.
DR Pfam; PF13726; Na_H_antiport_2; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007742};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 52..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..87
FT /note="Putative Na+/H+ antiporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13726"
FT DOMAIN 155..445
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 451 AA; 46146 MW; 8E9B5DA826C6041F CRC64;
MNAIVLAIVV MVGLCLARVS VVFSLVVAAL VGGLWAGMSV EQVISAFNDG LGGGATVALA
YATLGAFAVA LSRTGITTMV SDKALAWVGA RRDASQGGAG QAGGVKWLLF VALILVGAAS
GTVVPVHIAF IPILVPPLLG LMNLLQLDRR AVACVITFSI TIMYMTTPVG FGTIFLNDIL
TSSVNQAGEE LGMQVTTAMA PKAMLLPAAG MVLGLLVAVL FSYRRPRGYV SPLNEVKGEK
ASRPALSRKQ LVMIGVAIVG ALVVQLSTGS MVLGGLLGFA LLSMNGLFKW KDQDDVFTQG
MRLMALIGFI MIAASGFAGV MKASGAIPEL VAGSGALIGD NPGLAALVML LVGLFITMGI
GSSFSTIPII AAIYVPLAIS FGFSPLATLA LVGTAGALGD AGSPASDSTL GPTAGLNADG
QHDHIRDSVI PTFIHYNIPL VIFGWIAAHV L
//
