ID H2ISJ0_RAHAC Unreviewed; 285 AA.
AC H2ISJ0;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=RND family efflux transporter, MFP subunit {ECO:0000313|EMBL:AEX52638.1};
GN OrderedLocusNames=Rahaq2_2805 {ECO:0000313|EMBL:AEX52638.1};
OS Rahnella aquatilis (strain ATCC 33071 / DSM 4594 / JCM 1683 / NBRC 105701 /
OS NCIMB 13365 / CIP 78.65).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Rahnella.
OX NCBI_TaxID=745277 {ECO:0000313|EMBL:AEX52638.1, ECO:0000313|Proteomes:UP000009010};
RN [1] {ECO:0000313|EMBL:AEX52638.1, ECO:0000313|Proteomes:UP000009010}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33071 / DSM 4594 / JCM 1683 / NBRC 105701 / NCIMB 13365 /
RC CIP 78.65 {ECO:0000313|Proteomes:UP000009010};
RX PubMed=22582378; DOI=10.1128/JB.00380-12;
RA Martinez R.J., Bruce D., Detter C., Goodwin L.A., Han J., Han C.S.,
RA Held B., Land M.L., Mikhailova N., Nolan M., Pennacchio L., Pitluck S.,
RA Tapia R., Woyke T., Sobecky P.A.;
RT "Complete Genome Sequence of Rahnella aquatilis CIP 78.65.";
RL J. Bacteriol. 194:3020-3021(2012).
RN [2] {ECO:0000313|Proteomes:UP000009010}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33071 / DSM 4594 / JCM 1683 / NBRC 105701 / NCIMB 13365 /
RC CIP 78.65 {ECO:0000313|Proteomes:UP000009010};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Held B., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Sobecky P.,
RA Martinez R., Woyke T.;
RT "Complete sequence of chromosome of Rahnella aquatilis CIP 78.65.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP003244; AEX52638.1; -; Genomic_DNA.
DR RefSeq; WP_015697786.1; NZ_JMPO01000106.1.
DR AlphaFoldDB; H2ISJ0; -.
DR STRING; 745277.Rahaq2_2805; -.
DR GeneID; 61512832; -.
DR KEGG; raq:Rahaq2_2805; -.
DR PATRIC; fig|745277.3.peg.2685; -.
DR eggNOG; COG1566; Bacteria.
DR HOGENOM; CLU_018816_15_2_6; -.
DR OrthoDB; 9811754at2; -.
DR Proteomes; UP000009010; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0009636; P:response to toxic substance; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30367:SF13; MULTIDRUG RESISTANCE EFFLUX PUMP-RELATED; 1.
DR PANTHER; PTHR30367; P-HYDROXYBENZOIC ACID EFFLUX PUMP SUBUNIT AAEA-RELATED; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009010};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 43..230
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 84..148
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 285 AA; 31573 MW; 91594D327B50AEE7 CRC64;
MKFKTLKYFS TVLVFAVAIC AGWWMWNYYM QSPWTRDGKV RAEIVNITPE VSGRIIEINI
HDNQFVKSGY PLFSLDPVPF KIAVDNADAA VAKAAADLAK ANHEAHRRRG LGANIISAES
LDEANINAKA MQAAYQAAQA SLEQAKWNLS KTTIVAPADG YITNLQTRRG NYATAGTPLV
GLVDIHSFYI LGYFEETKLK NIREGSMADI TLFNGNTPLQ GRVESIGRAI YDQSLDTPED
LLMNVKPNVP WVRLAQRVPV RIKLENVPEH AVLVAGTTCT ISIRH
//
