ID H2IWZ2_RAHAC Unreviewed; 416 AA.
AC H2IWZ2;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=N-acetylmuramoyl-L-alanine amidase {ECO:0000256|ARBA:ARBA00011901};
DE EC=3.5.1.28 {ECO:0000256|ARBA:ARBA00011901};
GN OrderedLocusNames=Rahaq2_0899 {ECO:0000313|EMBL:AEX50804.1};
OS Rahnella aquatilis (strain ATCC 33071 / DSM 4594 / JCM 1683 / NBRC 105701 /
OS NCIMB 13365 / CIP 78.65).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Rahnella.
OX NCBI_TaxID=745277 {ECO:0000313|EMBL:AEX50804.1, ECO:0000313|Proteomes:UP000009010};
RN [1] {ECO:0000313|EMBL:AEX50804.1, ECO:0000313|Proteomes:UP000009010}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33071 / DSM 4594 / JCM 1683 / NBRC 105701 / NCIMB 13365 /
RC CIP 78.65 {ECO:0000313|Proteomes:UP000009010};
RX PubMed=22582378; DOI=10.1128/JB.00380-12;
RA Martinez R.J., Bruce D., Detter C., Goodwin L.A., Han J., Han C.S.,
RA Held B., Land M.L., Mikhailova N., Nolan M., Pennacchio L., Pitluck S.,
RA Tapia R., Woyke T., Sobecky P.A.;
RT "Complete Genome Sequence of Rahnella aquatilis CIP 78.65.";
RL J. Bacteriol. 194:3020-3021(2012).
RN [2] {ECO:0000313|Proteomes:UP000009010}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33071 / DSM 4594 / JCM 1683 / NBRC 105701 / NCIMB 13365 /
RC CIP 78.65 {ECO:0000313|Proteomes:UP000009010};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Held B., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Sobecky P.,
RA Martinez R., Woyke T.;
RT "Complete sequence of chromosome of Rahnella aquatilis CIP 78.65.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolyzes the link between N-acetylmuramoyl residues and L-
CC amino acid residues in certain cell-wall glycopeptides.; EC=3.5.1.28;
CC Evidence={ECO:0000256|ARBA:ARBA00001561};
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DR EMBL; CP003244; AEX50804.1; -; Genomic_DNA.
DR RefSeq; WP_015696072.1; NZ_JMPO01000130.1.
DR AlphaFoldDB; H2IWZ2; -.
DR STRING; 745277.Rahaq2_0899; -.
DR GeneID; 61511014; -.
DR KEGG; raq:Rahaq2_0899; -.
DR PATRIC; fig|745277.3.peg.850; -.
DR eggNOG; COG0860; Bacteria.
DR HOGENOM; CLU_014322_2_2_6; -.
DR OrthoDB; 9806267at2; -.
DR Proteomes; UP000009010; Chromosome.
DR GO; GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:UniProtKB-EC.
DR GO; GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
DR CDD; cd02696; MurNAc-LAA; 1.
DR Gene3D; 2.60.40.3500; -; 1.
DR Gene3D; 3.40.630.40; Zn-dependent exopeptidases; 1.
DR InterPro; IPR021731; AMIN_dom.
DR InterPro; IPR002508; MurNAc-LAA_cat.
DR NCBIfam; NF038267; amidase_AmiC; 1.
DR PANTHER; PTHR30404; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; 1.
DR PANTHER; PTHR30404:SF0; N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC; 1.
DR Pfam; PF01520; Amidase_3; 1.
DR Pfam; PF11741; AMIN; 1.
DR SMART; SM00646; Ami_3; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009010}.
FT DOMAIN 250..404
FT /note="MurNAc-LAA"
FT /evidence="ECO:0000259|SMART:SM00646"
SQ SEQUENCE 416 AA; 45991 MW; 07AE92B665A26C92 CRC64;
MTDDTHNPGR RRLLQTVAAS WMLSVSKVGF AASSQVIAVR IWPSSTYTRI TLESSTPLKY
KQFLLSDPSR VVVDIEGVHL NSVLKGLSEK VQQSDPYIRQ ARVGQFDTKT VRLVFELKRV
INPHVFTLKP VAEFHNRLVV DLYPQEGEIS AQDDPLLALL EDYNRGDVAR TLPPEKAKDG
QAGRSRPLVI MLDPGHGGED PGAIGKYKTR EKDVVLQIGR RLQKLIAREP NMKAHMTRNE
DVFIPLKVRV AKARKLRADL FISIHADAFT SRAAKGSSVF ALSTKGATSS AARFLAQTQN
ESDLIGGVSK SGDRYLDHTI FDLVQTATIS DSLKFGKEVL TRMGKINHLH KNKVDQAGFA
VLKAPDIPSI LVETAFISNI NEEKKLRTAH FQQQVAESIL AGIKAYFAEG GMSARA
//
