ID H2J0G4_RAHAC Unreviewed; 390 AA.
AC H2J0G4;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=RND family efflux transporter, MFP subunit {ECO:0000313|EMBL:AEX50013.1};
GN OrderedLocusNames=Rahaq2_0059 {ECO:0000313|EMBL:AEX50013.1};
OS Rahnella aquatilis (strain ATCC 33071 / DSM 4594 / JCM 1683 / NBRC 105701 /
OS NCIMB 13365 / CIP 78.65).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Rahnella.
OX NCBI_TaxID=745277 {ECO:0000313|EMBL:AEX50013.1, ECO:0000313|Proteomes:UP000009010};
RN [1] {ECO:0000313|EMBL:AEX50013.1, ECO:0000313|Proteomes:UP000009010}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33071 / DSM 4594 / JCM 1683 / NBRC 105701 / NCIMB 13365 /
RC CIP 78.65 {ECO:0000313|Proteomes:UP000009010};
RX PubMed=22582378; DOI=10.1128/JB.00380-12;
RA Martinez R.J., Bruce D., Detter C., Goodwin L.A., Han J., Han C.S.,
RA Held B., Land M.L., Mikhailova N., Nolan M., Pennacchio L., Pitluck S.,
RA Tapia R., Woyke T., Sobecky P.A.;
RT "Complete Genome Sequence of Rahnella aquatilis CIP 78.65.";
RL J. Bacteriol. 194:3020-3021(2012).
RN [2] {ECO:0000313|Proteomes:UP000009010}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33071 / DSM 4594 / JCM 1683 / NBRC 105701 / NCIMB 13365 /
RC CIP 78.65 {ECO:0000313|Proteomes:UP000009010};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Held B., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Sobecky P.,
RA Martinez R., Woyke T.;
RT "Complete sequence of chromosome of Rahnella aquatilis CIP 78.65.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP003244; AEX50013.1; -; Genomic_DNA.
DR RefSeq; WP_014333332.1; NZ_JMPO01000144.1.
DR AlphaFoldDB; H2J0G4; -.
DR STRING; 745277.Rahaq2_0059; -.
DR GeneID; 61510221; -.
DR KEGG; raq:Rahaq2_0059; -.
DR PATRIC; fig|745277.3.peg.58; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_14_1_6; -.
DR OrthoDB; 9791520at2; -.
DR Proteomes; UP000009010; Chromosome.
DR GO; GO:0019898; C:extrinsic component of membrane; IEA:InterPro.
DR GO; GO:1990195; C:macrolide transmembrane transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 6.10.140.1990; -; 1.
DR InterPro; IPR030190; MacA_alpha-hairpin_sf.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF33; EFFLUX PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009010};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 65..111
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT REGION 370..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..390
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 390 AA; 43016 MW; AC3A30A2EA62B986 CRC64;
MNVLRRYRVF SIASLTLCVF IAATALLIAH RTDNSATRHH IDVIGRGDIQ TTVMTTGVLQ
PLKKISVGAQ VNGQLKKLHV KQGDRVKKGQ LLAEIDPVIQ QNELRNAQAE LHSNRAQMQS
DKALLKQYQL ALTRQNKMAR DSAGVQSDLE SAQAQYDVQR EQLNMDAARV VQAEISVETA
KANLGYTRII APIDGEVLGI ITQEGQTIVS SQTAPTIMVL ADMSVMRIQT RISETDILKT
HPGQSVWFYV MADPTRRYES VMGAIQDAPE EALRESNESS GNTQQSTAVY YNGEFTISNE
QRRLKTSMTA EAYIIIGEVK NALLVPLTAV GERSPEGRYH VQVREKDKIT DRLIELGIRD
NKFAEVKSGL AQGDRVVSTT SAPGDADASQ
//
