ID H2J5C0_MARPK Unreviewed; 582 AA.
AC H2J5C0;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Oligoendopeptidase F {ECO:0000313|EMBL:AEX84978.1};
GN OrderedLocusNames=Marpi_0537 {ECO:0000313|EMBL:AEX84978.1};
OS Marinitoga piezophila (strain DSM 14283 / JCM 11233 / KA3).
OC Bacteria; Thermotogota; Thermotogae; Petrotogales; Petrotogaceae;
OC Marinitoga.
OX NCBI_TaxID=443254 {ECO:0000313|EMBL:AEX84978.1, ECO:0000313|Proteomes:UP000007161};
RN [1] {ECO:0000313|EMBL:AEX84978.1, ECO:0000313|Proteomes:UP000007161}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14283 / JCM 11233 / KA3
RC {ECO:0000313|Proteomes:UP000007161};
RX PubMed=23045491; DOI=10.1128/JB.01430-12;
RA Lucas S., Han J., Lapidus A., Cheng J.F., Goodwin L.A., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N.C., Ivanova N., Pagani I., Vannier P.,
RA Oger P., Bartlett D.H., Noll K.M., Woyke T., Jebbar M.;
RT "Complete Genome Sequence of the Thermophilic, Piezophilic, Heterotrophic
RT Bacterium Marinitoga piezophila KA3.";
RL J. Bacteriol. 194:5974-5975(2012).
RN [2] {ECO:0000313|Proteomes:UP000007161}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14283 / JCM 11233 / KA3
RC {ECO:0000313|Proteomes:UP000007161};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Jebbar M.,
RA Vannier P., Oger P., Cario A., Bartlett D., Noll K.M., Woyke T.;
RT "Complete sequence of chromosome of Marinitoga piezophila KA3.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU003435};
CC Note=Binds 1 zinc ion. {ECO:0000256|RuleBase:RU003435};
CC -!- SIMILARITY: Belongs to the peptidase M3 family.
CC {ECO:0000256|RuleBase:RU003435}.
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DR EMBL; CP003257; AEX84978.1; -; Genomic_DNA.
DR RefSeq; WP_014296050.1; NC_016751.1.
DR AlphaFoldDB; H2J5C0; -.
DR STRING; 443254.Marpi_0537; -.
DR KEGG; mpz:Marpi_0537; -.
DR eggNOG; COG1164; Bacteria.
DR HOGENOM; CLU_021290_3_0_0; -.
DR OrthoDB; 9769691at2; -.
DR Proteomes; UP000007161; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd09610; M3B_PepF; 1.
DR Gene3D; 1.10.1370.20; Oligoendopeptidase f, C-terminal domain; 1.
DR Gene3D; 1.20.140.70; Oligopeptidase f, N-terminal domain; 1.
DR InterPro; IPR013647; OligopepF_N_dom.
DR InterPro; IPR042088; OligoPept_F_C.
DR InterPro; IPR045090; Pept_M3A_M3B.
DR InterPro; IPR001567; Pept_M3A_M3B_dom.
DR PANTHER; PTHR11804:SF5; OLIGOENDOPEPTIDASE F; 1.
DR PANTHER; PTHR11804; PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED; 1.
DR Pfam; PF01432; Peptidase_M3; 1.
DR Pfam; PF08439; Peptidase_M3_N; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003435};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU003435};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000256|RuleBase:RU003435};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU003435};
KW Reference proteome {ECO:0000313|Proteomes:UP000007161};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU003435}.
FT DOMAIN 109..175
FT /note="Oligopeptidase F N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08439"
FT DOMAIN 194..572
FT /note="Peptidase M3A/M3B catalytic"
FT /evidence="ECO:0000259|Pfam:PF01432"
FT COILED 14..62
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 582 AA; 68058 MW; D9A66095CB4234AC CRC64;
MKWDLTFFYD SPENEQIKKD FENALEGAKK LKEKYYPILS SKELSAKEVK NFLEELEKLI
EKPYFAMQYA SLLYSANTQD KTAQKLVAMG QDYLTKGEME LSFWKPVLLS HSLEKLEELK
NSPELEKYKH VLEVLIEEKP HVLSEDAEKA LSALEPAGRR AFSKLYEKLV SSYTFEIEID
GELKTMTGAE IRSLRQHPDK DLRQKAMKMF FERYEKDKII LESTFNSVAK YYDTESKLRN
YPEPISMRNM ANEVKDEIVK MVIDVTTEQT PIVHKYYKWK RDFLGYDITL ADIYAPLKPV
KKEISFEDAK KLVLDAYYEF DKEIGDIVKS FFDENRIDSE IQPGKRGGAF CSYNIPNYKP
FILLNYTGNM RDVMTLAHEL GHGVHGTLSS KQSLLNYHTP LTMAEVASVF GEMLVMDKLL
KELEGEEKQM FIASKIEDMF ATMFRQNMFA RFEIQSHKMI DENGMASWEE LSELYEKELK
IMFGDSVKIP EEYKYEWSTI PHMLAVPFYV YAYNFANLLV IALYEKYLEE GKAFIPKYKE
LLSSGGNAAP EKLLEKLDID ITKKEFWEKG FKYIERELIN KL
//
