ID H2KQ14_CLOSI Unreviewed; 531 AA.
AC H2KQ14;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Kinesin family member C2/C3 {ECO:0000313|EMBL:GAA29231.2};
GN ORFNames=CLF_103034 {ECO:0000313|EMBL:GAA29231.2};
OS Clonorchis sinensis (Chinese liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA29231.2, ECO:0000313|Proteomes:UP000008909};
RN [1] {ECO:0000313|EMBL:GAA29231.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Henan {ECO:0000313|EMBL:GAA29231.2};
RX PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA Yu X.;
RT "The draft genome of the carcinogenic human liver fluke Clonorchis
RT sinensis.";
RL Genome Biol. 12:R107-R107(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Henan;
RA Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA Wu Z., Yu X.;
RT "The genome and transcriptome sequence of Clonorchis sinensis provide
RT insights into the carcinogenic liver fluke.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR EMBL; DF142957; GAA29231.2; -; Genomic_DNA.
DR AlphaFoldDB; H2KQ14; -.
DR Proteomes; UP000008909; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47972:SF16; KINESIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR47972; KINESIN-LIKE PROTEIN KLP-3; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000008909}.
FT DOMAIN 182..500
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT COILED 103..161
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 262..269
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 531 AA; 59969 MW; 39A15805B9758D21 CRC64;
MPIFPKVNEG KDLGVPAEPG HEKIWHISSK ISHVDRPVSE VARSTIASKR TTVARAFSRL
GGFSGRPTLD IGESTSTIWG DETEHRVEVP ITDAERLAWE HVRTQMNQKL REKEEEVSKW
RKLAKELECE LEELKQKTLT EVQMEEEIRA LNEENAILVE HYLAEMVLRK KYLNMIQDLK
GKIRVFCRIR PAVLTEVTRK NPIVVYTPDK HTALVKVSRG LKVFQFDRVF GPNATQEDLF
EETTNLVQSV IDGYNVCIFA YGATGTGKTY TLAGDRERPG LVFHCVDYLF ELLDDPLFRT
KSYSDVSVSI MEMYDEKILD LLVDYGTHED LPIQPDNNGV MYVEGVVQKQ TACAAELYEL
YQRAWHNRRM AETRLEHNST RSHFILSIMV MVTNKITKTT YRGKLTVIDM AGSERATTTG
STGESLKDTD QSLVALGDVI TSLTLSQPTV PYESSKLTKL MQDSLGGNAK TLMIINVNET
EAKMPETINS LNYGSRLKTV DNQANPTSNS EQVAKLKVLT EKLKKGEPDP C
//
