ID H2KSR0_CLOSI Unreviewed; 453 AA.
AC H2KSR0;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Uncharacterized aarF domain-containing protein kinase 5 {ECO:0000313|EMBL:GAA30503.2};
GN ORFNames=CLF_109971 {ECO:0000313|EMBL:GAA30503.2};
OS Clonorchis sinensis (Chinese liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA30503.2, ECO:0000313|Proteomes:UP000008909};
RN [1] {ECO:0000313|EMBL:GAA30503.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Henan {ECO:0000313|EMBL:GAA30503.2};
RX PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA Yu X.;
RT "The draft genome of the carcinogenic human liver fluke Clonorchis
RT sinensis.";
RL Genome Biol. 12:R107-R107(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Henan;
RA Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA Wu Z., Yu X.;
RT "The genome and transcriptome sequence of Clonorchis sinensis provide
RT insights into the carcinogenic liver fluke.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. ADCK protein
CC kinase family. {ECO:0000256|ARBA:ARBA00009670}.
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DR EMBL; DF143467; GAA30503.2; -; Genomic_DNA.
DR AlphaFoldDB; H2KSR0; -.
DR Proteomes; UP000008909; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd13969; ADCK1-like; 1.
DR InterPro; IPR004147; ABC1_dom.
DR InterPro; IPR045307; ADCK1_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR43173:SF43; AARF DOMAIN-CONTAINING KINASE 5; 1.
DR PANTHER; PTHR43173; ABC1 FAMILY PROTEIN; 1.
DR Pfam; PF03109; ABC1; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:GAA30503.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000008909};
KW Transferase {ECO:0000313|EMBL:GAA30503.2}.
FT DOMAIN 22..278
FT /note="ABC1 atypical kinase-like"
FT /evidence="ECO:0000259|Pfam:PF03109"
SQ SEQUENCE 453 AA; 52045 MW; 592811C70D0C060F CRC64;
MGQGLVSLNH VLPKQYTETL ERLHDQALVR TAEEVDRIFL EDFGKTPSEV FASFDPEPIA
AASLAQVHRA VTKAGERVAV KVQYEDLRDR FHGDIHTLEF LLRLVEYVHP NFGFAWVLQD
MRKTLAKELD FENEADNAEK CALHLTHLGT LRPDGAVHIP RVNRELTSKR VLTAEFIDGI
KANEVSALRE AGFCLADLDK LLVRVFSYQV FCTGFVHADP HPGNLLIRKR PLSDPRPRWF
LVLLDHGLYD SLPHNQRISL CEMYRAILDC NEEGMKKASS ELGVQDWATF GDVILQKPWR
RKTLYLPAHL TEADRMFLRA TAAEHFDRVM AVLQQVPRPM LLFIRNLNLI RSICRLHGDP
IDRYVLMVDS AVLGSYSTHE PSGKCRSLSW GRALRVQLTL QHYHWQLRIE CFFNWIRFML
YRLLRFMGRA PDLEELQSLV ADVAANAPNS FLV
//
