ID   H2KVJ7_CLOSI            Unreviewed;       973 AA.
AC   H2KVJ7;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=Suppressor of fused homolog {ECO:0000313|EMBL:GAA31346.2};
GN   ORFNames=CLF_112522 {ECO:0000313|EMBL:GAA31346.2};
OS   Clonorchis sinensis (Chinese liver fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX   NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA31346.2, ECO:0000313|Proteomes:UP000008909};
RN   [1] {ECO:0000313|EMBL:GAA31346.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Henan {ECO:0000313|EMBL:GAA31346.2};
RX   PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA   Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA   Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA   Yu X.;
RT   "The draft genome of the carcinogenic human liver fluke Clonorchis
RT   sinensis.";
RL   Genome Biol. 12:R107-R107(2011).
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DR   EMBL; DF144657; GAA31346.2; -; Genomic_DNA.
DR   AlphaFoldDB; H2KVJ7; -.
DR   Proteomes; UP000008909; Unassembled WGS sequence.
DR   Gene3D; 3.30.1360.230; Sufu, C-terminal domain; 1.
DR   InterPro; IPR020941; SUFU-like_domain.
DR   InterPro; IPR024314; SUFU_C.
DR   InterPro; IPR038489; SUFU_C_sf.
DR   InterPro; IPR037181; SUFU_N.
DR   InterPro; IPR007768; Suppressor_of_fused.
DR   PANTHER; PTHR10928; SUPPRESSOR OF FUSED; 1.
DR   PANTHER; PTHR10928:SF2; SUPPRESSOR OF FUSED HOMOLOG; 1.
DR   Pfam; PF05076; SUFU; 2.
DR   Pfam; PF12470; SUFU_C; 1.
DR   SUPFAM; SSF103359; Suppressor of Fused, N-terminal domain; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008909}.
FT   DOMAIN          63..167
FT                   /note="Suppressor of fused-like"
FT                   /evidence="ECO:0000259|Pfam:PF05076"
FT   DOMAIN          233..342
FT                   /note="Suppressor of fused-like"
FT                   /evidence="ECO:0000259|Pfam:PF05076"
FT   DOMAIN          637..756
FT                   /note="Suppressor of fused C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12470"
FT   REGION          166..198
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          396..475
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          595..626
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          795..843
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          947..973
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        172..188
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        407..451
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        795..822
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   973 AA;  105239 MW;  F2F417A6B77D317F CRC64;
     MANSAFGPVV GPTTFPVSNV GPHPTRDEQA LGLKVIYNVC RNLYPDQPTP LQVTALRKFW
     MGGPDPLDFI NMYSNPGSTE LRSPPHWHYV SNGLSDLYGD SRLHNQCASV DEPSGFGFEL
     TLRIRREPTE AHPPTWPAHL LQSLARYVFH SQAQLMVGDH IPWPSALDKQ PYPPSPQQEQ
     MDGSVRDSRS TQKPTEADAH SIAVAAAATA ASILATNGTK SGESRMAALA NPNIYASMVA
     AALAAVQSTT NSQLRSQSGC KTEPKPGTVE GESRIHHMLV VEDPQLKRIS TPYGYVQFLQ
     LVGLCEEELR LVQRWTGNRV IDIMRRLPET GGGLLVTDMK RKLSLFELEP KLADYVNEQL
     RIEGSNLSGV TTQYFAWAPI SLSTLGEILP GELEARRHRH PESDHALSKP YSSSVGGSQA
     IDPTTASSSE QLDATSAPTD LSVSRLINSD QKARLSPGPV AMETEDTVVS SSTKKDMDED
     DFVDVVGDSG PSSLVNAKVA TTTNEMDALD TPKSLINDVT SLPTSSVQSC STQSTSAPGT
     FSAWCARIPN SATTENSKFS TPSDIIGSLP ETSYGPSDLI SPLTGPLGFR TFGNPSPACP
     VNNGPRGGSH DQRGAHTPGS TGEGSAPCTP LAHLSLSPAS LELLPTRVID CLDVHLCREA
     GEMLPLAVND RLRHGKHFTF LNSHFPDHAI TLVPSGVTGA FVTEENPYVA RGPWLQILFP
     EDFLESLEFQ FTCLQRADDL ALPIVFRWPE RRLRICLVEP SPALNSCLAN QNSSYNLPTP
     RSLLPKAVTM NSPDGIRNWG NLNSPSNKPD VNVPSSAVRS PRSFSIPRPD HPPQPRPEDH
     VAPPHLLPYF PPGCVPPPAM LAAMFSTSSP MHFQGPSHQP SGIGSQPQTD RSLIGPNQTV
     FDAKSNWMQF FNSFMNKRET TSGAISPPFI AISEAMNAAM GAMQHAGPRY NPSVARAGNR
     PTTPRSHETE PPA
//