ID H2KZ95_CAEEL Unreviewed; 352 AA.
AC H2KZ95;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Protein-tyrosine phosphatase {ECO:0000313|EMBL:CCD67071.1};
GN ORFNames=CELE_Y48G9A.9 {ECO:0000313|EMBL:CCD67071.1}, Y48G9A.9
GN {ECO:0000313|EMBL:CCD67071.1, ECO:0000313|WormBase:Y48G9A.9a};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD67071.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCD67071.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD67071.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284603; CCD67071.1; -; Genomic_DNA.
DR RefSeq; NP_001022892.1; NM_001027721.3.
DR AlphaFoldDB; H2KZ95; -.
DR SMR; H2KZ95; -.
DR EPD; H2KZ95; -.
DR PeptideAtlas; H2KZ95; -.
DR EnsemblMetazoa; Y48G9A.9a.1; Y48G9A.9a.1; WBGene00021702.
DR GeneID; 175343; -.
DR KEGG; cel:CELE_Y48G9A.9; -.
DR AGR; WB:WBGene00021702; -.
DR WormBase; Y48G9A.9a; CE27280; WBGene00021702; -.
DR HOGENOM; CLU_001645_9_4_1; -.
DR OMA; KRAQCIQ; -.
DR OrthoDB; 2914248at2759; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00021702; Expressed in larva and 3 other cell types or tissues.
DR ExpressionAtlas; H2KZ95; baseline and differential.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IBA:GO_Central.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR GO; GO:0008045; P:motor neuron axon guidance; IBA:GO_Central.
DR CDD; cd00047; PTPc; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR46163:SF2; TYROSINE-PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR46163; TYROSINE-PROTEIN PHOSPHATASE-RELATED; 1.
DR Pfam; PF00102; Y_phosphatase; 1.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:H2KZ95,
KW ECO:0007829|PeptideAtlas:H2KZ95};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940}.
FT DOMAIN 63..323
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 261..314
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 352 AA; 40434 MW; 8A3D9D0B0EC15958 CRC64;
MLKIFGDKKG KEKKGKNNNN VNEKRPASAQ SSNGTETDDH HRKYVETLNN FIIATEKLGI
EGLAKQYRKL DAQQDSSLTF EAFKQNMHKN RYSDVVCRDT TRVKLTIDKS RYEDYIHANY
VKTNYLRNTF ICTQGPLQHT IIDFWRMIFQ ERAESILMLC KTMEEGRPKC VGYWPSLGVT
ETYGCIRVTN MGESSDEFEI CNLAVTFVPD NVPVDEQPAN LKELRVNLIK WPNWPDRGVP
DEKCHTVPQR LLAQVRHGPC VVHCSAGIGR TGCVVALEFA YNKLDRGLKV DFEEIITELR
KQRAQCIQTE IQYLYIHRVM IAFARGETDV SEKALAAADA FLKSYDEHLK KI
//
