ID H2L3X5_ORYLA Unreviewed; 216 AA.
AC H2L3X5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Calpain, small subunit 1 b {ECO:0000313|Ensembl:ENSORLP00000000455.1};
GN Name=capns1a {ECO:0000313|Ensembl:ENSORLP00000000455.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000000455.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000000455.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000000455.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000000455.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000000455.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_004076077.1; XM_004076029.2.
DR AlphaFoldDB; H2L3X5; -.
DR STRING; 8090.ENSORLP00000000455; -.
DR Ensembl; ENSORLT00000000455.2; ENSORLP00000000455.1; ENSORLG00000000369.2.
DR GeneID; 101165748; -.
DR KEGG; ola:101165748; -.
DR CTD; 550598; -.
DR eggNOG; KOG0037; Eukaryota.
DR GeneTree; ENSGT00940000155478; -.
DR HOGENOM; CLU_051357_2_0_1; -.
DR InParanoid; H2L3X5; -.
DR OMA; MCRAFQT; -.
DR OrthoDB; 4075143at2759; -.
DR TreeFam; TF314682; -.
DR Proteomes; UP000001038; Chromosome 14.
DR Bgee; ENSORLG00000000369; Expressed in testis and 14 other cell types or tissues.
DR GO; GO:0110158; C:calpain complex; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd16188; EFh_PEF_CPNS1_2; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR46735; CALPAIN, SMALL SUBUNIT 1 A-RELATED; 1.
DR PANTHER; PTHR46735:SF3; CALPAIN, SMALL SUBUNIT 1 A-RELATED; 1.
DR Pfam; PF13833; EF-hand_8; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 117..152
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 19..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 216 AA; 24611 MW; 97F9F5CED39B6A4D CRC64;
MFLLKKVISG VVDVVSNIDP AQFAPSDPPP PRRPLAYAEQ NESEEDKQFR RVFKQLAGDD
MEVSPPELMN ILNKIISKHG DLKTDGFSIE SCRSMVAVMD SDSTGKLGFD EFKYLWNNIK
KWQAVYKTFD SDHSGLISAD ELPRAFTAAG FPLNDQLFQM IIRRYSDENG NMDFDNYIGC
LVRLDAMCRA FKTLDKDDNG TIKVNIKEWL QLTMYS
//
