ID H2L684_ORYLA Unreviewed; 619 AA.
AC H2L684;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=Tenascin XB {ECO:0008006|Google:ProtNLM};
GN Name=LOC101155444 {ECO:0000313|Ensembl:ENSORLP00000001328.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000001328.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000001328.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000001328.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000001328.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000001328.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR AlphaFoldDB; H2L684; -.
DR Ensembl; ENSORLT00000001329.2; ENSORLP00000001328.2; ENSORLG00000001075.2.
DR eggNOG; KOG1225; Eukaryota.
DR eggNOG; KOG2579; Eukaryota.
DR GeneTree; ENSGT00940000155188; -.
DR HOGENOM; CLU_001162_0_0_1; -.
DR TreeFam; TF329915; -.
DR Proteomes; UP000001038; Chromosome 11.
DR Bgee; ENSORLG00000001075; Expressed in muscle tissue and 7 other cell types or tissues.
DR CDD; cd00063; FN3; 2.
DR CDD; cd00087; FReD; 1.
DR Gene3D; 3.90.215.10; Gamma Fibrinogen, chain A, domain 1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR036056; Fibrinogen-like_C.
DR InterPro; IPR014716; Fibrinogen_a/b/g_C_1.
DR InterPro; IPR002181; Fibrinogen_a/b/g_C_dom.
DR InterPro; IPR020837; Fibrinogen_CS.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR NCBIfam; NF040941; GGGWT_bact; 1.
DR PANTHER; PTHR46708; TENASCIN; 1.
DR PANTHER; PTHR46708:SF3; TENASCIN-X; 1.
DR Pfam; PF00147; Fibrinogen_C; 1.
DR Pfam; PF00041; fn3; 2.
DR SMART; SM00186; FBG; 1.
DR SMART; SM00060; FN3; 2.
DR SUPFAM; SSF56496; Fibrinogen C-terminal domain-like; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR PROSITE; PS00514; FIBRINOGEN_C_1; 1.
DR PROSITE; PS51406; FIBRINOGEN_C_2; 1.
DR PROSITE; PS50853; FN3; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Secreted {ECO:0000256|ARBA:ARBA00022530}.
FT DOMAIN 193..282
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 399..612
FT /note="Fibrinogen C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51406"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 126..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..60
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 619 AA; 68739 MW; 0D0B41DF91790A87 CRC64;
MEREDNSLID TEKTSEFHFQ KEKTNSEGVG EKYKGISSHQ TNYSEETIIN PESEKTVGAT
KDATSAGEPL EFVKVTNRST DGFTLTLGTP EGKFGHFVVS STEAKKAEEL PRKEAEQNNL
TQEPKNGAIV DDNYVGRSTN GAKPTESKTV QPGSAQLHQF KDLPSQTQYN VPLPGMGPGL
QSSQHKLVIS PEPPTNIAFS KVTENSLTVS WTKPRSRVSG FKVTYTHADE GEPVSVTLDS
GDSSLDLSRL SPGSTYEVTI ISTLGLDESD PIRDSVMTLP DPPTDLRAIN VTDSTALLLW
RPALAAVYKY AIVYGSETGR DADGPRDLLA TNVTPRTAVL SWKPPSKPAQ RYLLTYRTQG
QEIKYNLTRL HPGSLYSVQL IAIRGQHRPS ISTTFTTGIL KYPYPTDCTQ ELLNGIRTSG
EVEIFPQGKL GTPMVVYCDM ETDGGGWMVF QRRKDGSEDF FRGWKDYVKG FGNLNGEFWF
GLEKLHNLST MAKMILRVDL RDGGESVFAK YSTFEVAKKY YRLKVGGYSG TAGDSLSYHN
NQVFSTKDRN PAPSITSCAM SYRGGWWYMN CHEANLNGLY GIDVKHQGII WTSWKGKDHS
IQFTEMKMRP ADFRPPPKK
//
