ID H2L8F6_ORYLA Unreviewed; 742 AA.
AC H2L8F6;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Cytoplasmic polyadenylation element binding protein 4 {ECO:0000313|Ensembl:ENSORLP00000002128.2};
GN Name=CPEB4 {ECO:0000313|Ensembl:ENSORLP00000002128.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000002128.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000002128.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000002128.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000002128.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000002128.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RRM CPEB family.
CC {ECO:0000256|ARBA:ARBA00010347}.
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DR RefSeq; XP_011481506.1; XM_011483204.1.
DR Ensembl; ENSORLT00000002129.2; ENSORLP00000002128.2; ENSORLG00000001711.2.
DR Ensembl; ENSORLT00000036951.1; ENSORLP00000044943.1; ENSORLG00000001711.2.
DR eggNOG; KOG0129; Eukaryota.
DR GeneTree; ENSGT00940000154998; -.
DR HOGENOM; CLU_014948_2_1_1; -.
DR TreeFam; TF317658; -.
DR Proteomes; UP000001038; Chromosome 14.
DR Bgee; ENSORLG00000001711; Expressed in testis and 15 other cell types or tissues.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:InterPro.
DR GO; GO:0045182; F:translation regulator activity; IEA:InterPro.
DR CDD; cd19757; Bbox1; 1.
DR CDD; cd12724; RRM1_CPEB2_like; 1.
DR CDD; cd12726; RRM2_CPEB2_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 4.10.640.40; Cytoplasmic polyadenylation element-binding protein, ZZ domain; 1.
DR InterPro; IPR032296; CEBP_ZZ.
DR InterPro; IPR038446; CEBP_ZZ_sf.
DR InterPro; IPR034819; CPEB.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR12566; CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB; 1.
DR PANTHER; PTHR12566:SF2; CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 4; 1.
DR Pfam; PF16366; CEBP_ZZ; 1.
DR Pfam; PF16367; RRM_7; 1.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 485..572
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 593..671
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 45..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 81..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 225..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..277
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..369
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 742 AA; 81003 MW; D1A2AE9B68A04F20 CRC64;
MGDYGFGVLV QNNTGNKSAF PVRIHPHLQP PHHHQNVSQS PAAFINSTTA TGNGSTGGSP
WLFSNSATHN SVQDEILGGA EKPKAQQQQE MQESQEKQQL SPGSHQEGGS NGGIISELEK
AKETKTENGT SEGGNGKEKQ LRLESPVLTG FDYQETSGLG GTGPVQSSTT SSSLTGFNNW
SAAIPPAPST IINEDVSFFN PVSANNGTLL FQNFSHHVSP GFGGNFSPQI GPAAALSQHH
PAPPPHPHFQ HPHNQHQQHR RSPASPHPPP PFPHRNPAFS QLPHLSNSLN KPPSPWGSAS
YQSPSPSPGS STSWSPGGGY GSGGGGWGGS QGRDYRRGLN GGMTPINSIS PLKKTFPNNH
VTSQKYPRNG PAGFNPKSWI DDGVSRSDNI FPFQERTRSF DSFNMNTLES SLIDIMRAEQ
DTLKGRLGFP HPGGDNPLPL NGHSSLFPME DGFPDEERGD QGLPGLGSPH CFPHQNGERV
ERYSRKVFVG GLPPDIDEDE ITASFRRFGH LFVDWPHKAE SKSYFPPKGY AFLLFQDESS
VQALIDACIE EDGKLYLCVS SPTIKDKPVQ IRPWNLNDSD FVMDGSQPLD PRKTIFVGGV
PRPLRAVELA MIMDRLYGGV CYAGIDTDPE LKYPKGAGRV AFSNQQSYIA AISARFVQLQ
HGEIDKRVEV KPYVLDDQLC DECQGTRCGG KFAPFFCANV TCLQYYCEYC WAAIHSRAGR
EFHKPLVKEG GDRPRHISFR WN
//
