ID H2LDU3_ORYLA Unreviewed; 616 AA.
AC H2LDU3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Septin 9b {ECO:0000313|Ensembl:ENSORLP00000004107.2};
GN Name=septin9b {ECO:0000313|Ensembl:ENSORLP00000004107.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000004107.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000004107.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000004107.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000004107.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000004107.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. Septin GTPase family.
CC {ECO:0000256|RuleBase:RU004560}.
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DR AlphaFoldDB; H2LDU3; -.
DR STRING; 8090.ENSORLP00000004107; -.
DR Ensembl; ENSORLT00000004108.2; ENSORLP00000004107.2; ENSORLG00000003303.2.
DR eggNOG; KOG1547; Eukaryota.
DR GeneTree; ENSGT00940000157195; -.
DR HOGENOM; CLU_017718_7_1_1; -.
DR InParanoid; H2LDU3; -.
DR OrthoDB; 5396944at2759; -.
DR TreeFam; TF101078; -.
DR Proteomes; UP000001038; Chromosome 1.
DR Bgee; ENSORLG00000003303; Expressed in testis and 14 other cell types or tissues.
DR GO; GO:0032153; C:cell division site; IBA:GO_Central.
DR GO; GO:0015630; C:microtubule cytoskeleton; IBA:GO_Central.
DR GO; GO:0031105; C:septin complex; IBA:GO_Central.
DR GO; GO:0005940; C:septin ring; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0060090; F:molecular adaptor activity; IBA:GO_Central.
DR GO; GO:0061640; P:cytoskeleton-dependent cytokinesis; IBA:GO_Central.
DR CDD; cd01850; CDC_Septin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030379; G_SEPTIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016491; Septin.
DR InterPro; IPR008114; Septin3.
DR PANTHER; PTHR18884; SEPTIN; 1.
DR PANTHER; PTHR18884:SF47; SEPTIN-9; 1.
DR Pfam; PF00735; Septin; 1.
DR PRINTS; PR01741; SEPTIN3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51719; G_SEPTIN; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU004560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004560};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 298..570
FT /note="Septin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51719"
FT REGION 28..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 67..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 206..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 571..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..83
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..122
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..150
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..174
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..189
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 594..608
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 616 AA; 69133 MW; 0F42F590228307FF CRC64;
MSESGVNPHL EGIISDFEAL KRSFEVEDVE TSSHSSPGSR RTTNSPHRNA MSPTSIYYRD
LGTASTATNN NNLNYTQPRS IMGGGGSKTP EPVSRRSELS IDISSPSKQV DNVTSPASTR
FGSSGALKRP EVLGHSKTAE TSHKREVTFA KTPSDSPVIR RSEANNNNNG INRTHEQNHS
RKLEPPSPAD LRKPDISITR APLENNGHHT AVHHPHHPNP HHNTIVTTIR CSSPNHAGRK
SPNPDRSEVS LSHSNMSESA KPHPPSSQAK GEKSHAGEFG YVGIDAILEQ MRRKAMKQGF
ELNIMVVGQS GLGKSTLMNT LFKSKVSRKS AQPNPEERIP KTIEIKSISH DIEEKGVRMK
LTVIDTPGFG DHINNENCWQ PIMKFINDQY EAYLQEEINI NRKKKIPDSR VHCCIYFIPP
TGHCLRPLDV EFMRRLSKVV NIVPVIAKAD TLTLEERDYF KQKIREELRA NEIDVYPQKE
FDEDAEDRMI NDKIREMIPF AVVGSDQEYQ VNGKRILGRK TKWGTIEVEN IAHCEFAYLR
DLLIRTHMQN IKDITSSIHF ETYRVRRLNE SNGLPHHHLP DDLSADPKAN GQLEEQPSAP
QTNGAAAQHE ALSHEM
//
