ID H2LG94_ORYLA Unreviewed; 565 AA.
AC H2LG94;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Forkhead box J3 {ECO:0000313|Ensembl:ENSORLP00000004987.2};
GN Name=FOXJ3 {ECO:0000313|Ensembl:ENSORLP00000004987.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000004987.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000004987.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000004987.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000004987.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000004987.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR AlphaFoldDB; H2LG94; -.
DR Ensembl; ENSORLT00000004988.2; ENSORLP00000004987.2; ENSORLG00000026457.1.
DR eggNOG; KOG2294; Eukaryota.
DR GeneTree; ENSGT00940000160362; -.
DR HOGENOM; CLU_077699_1_2_1; -.
DR TreeFam; TF316127; -.
DR Proteomes; UP000001038; Chromosome 5.
DR Bgee; ENSORLG00000026457; Expressed in muscle tissue and 13 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd20024; FH_FOXJ2-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR045912; FOXJ2/3-like.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46078; FORKHEAD BOX PROTEIN J2 FAMILY MEMBER; 1.
DR PANTHER; PTHR46078:SF5; FORKHEAD BOX PROTEIN J3; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 62..132
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 62..132
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 195..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 260..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..387
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 565 AA; 62685 MW; A7C8C891C5F18B15 CRC64;
MTSELESSLT SMDWLPQLTM QAAIRKADAQ NAHGPGMGKK STLLDHNTTL DQEEVQQHKD
GKPPYSYASL ITFAINSSPK KKMTLSEIYQ WICDNFPYYR EAGSGWKNSI RHNLSLNKCF
LKVARSKDDP GKVRVKVAFN AVTISKGNRS LMFMFQVALY NTEQEGSDSP RSSLNNSLSD
QSLASVNLNS VSSVHSYTPV TSHPEPVSQS MSLQQQAPQS QYSMPDRDKQ LLFSDFENLS
ASFRSLYKSV FEQSFSHQGL MGMPSDSSQQ THTSCSYQHS PSGTINTQNS LSNNQPNSHP
NNHSTTGGQV PLSHPAQAHP GHGSPHAQHL PQHGGPHNQH SQHSQHPQHA PQQQHTQHPS
QHTQHSQHPS QHGQQHQSLS HQTHPTQQQM ACSTGLLSDW CPNVDALKET CRIASSFNWA
DVDLSPFQGL KESMRQADLN NWCLEPTQIA DLCSSINQFF TRTGVIPPQG AVQPPVCHGS
MHTNKPSQHL NAGNLYVGSK PNMPMTGPPG YPHMPPMSTA GPTMTGHHAQ MNQQHMMPSR
SFQMHRMPPD DAPDVDEFDW DSIVY
//
