ID H2LGY2_ORYLA Unreviewed; 424 AA.
AC H2LGY2;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Zgc:154075 {ECO:0000313|Ensembl:ENSORLP00000005235.2};
GN Name=zgc:154075 {ECO:0000313|Ensembl:ENSORLP00000005235.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000005235.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000005235.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000005235.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000005235.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000005235.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family.
CC {ECO:0000256|ARBA:ARBA00010928}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H2LGY2; -.
DR Ensembl; ENSORLT00000005236.2; ENSORLP00000005235.2; ENSORLG00000004182.2.
DR eggNOG; ENOG502QQXH; Eukaryota.
DR GeneTree; ENSGT00390000004367; -.
DR HOGENOM; CLU_023194_4_2_1; -.
DR TreeFam; TF334260; -.
DR Proteomes; UP000001038; Chromosome 7.
DR Bgee; ENSORLG00000004182; Expressed in intestine and 13 other cell types or tissues.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43377; BILIVERDIN REDUCTASE A; 1.
DR PANTHER; PTHR43377:SF2; ZGC:154075; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 6..128
FT /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01408"
FT DOMAIN 140..345
FT /note="Gfo/Idh/MocA-like oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02894"
SQ SEQUENCE 424 AA; 47171 MW; 8A8DA4BCBD14BD21 CRC64;
MTATVRAIVI GAGCRGAGYS EFALIHPERM KVVAVADPRK FARTNLQQQH QIENENVFED
WQSVADREKF ADAVLICTPD RLHKDPAVAF AKKGYHILLE KPLATTAEDC RAIVEACMQS
NVMLSVGHVL RYDPVTYKIK ELIDAGVIGD VVHIQHLEPV GFYHFAHSFV RGNWRNEAES
SFALLAKSCH DIDLIHHWAG ARRYLSSVSS HQPTGAGDRC LNCSIEKDCP YSACKIYLER
VKQGHTRWPV SVICPNSLPD IESVTEALRT GPYGRCVYEC DNDVCSNQVV NMEFEGGLTA
AFSMVAFTEE ICQRKTTIYG SKGELSCDGH QICVFDFLTQ KSTKITASRE APGHFGKGGH
GAADYHLIDA FISAVANNDP SQIRCGSEET LTSHLLVFEA ERSRLESRVV FCEDGRKQKT
REQQ
//
