ID H2LHQ2_ORYLA Unreviewed; 565 AA.
AC H2LHQ2;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=XK-related protein {ECO:0000256|RuleBase:RU910716};
GN Name=LOC101168926 {ECO:0000313|Ensembl:ENSORLP00000005516.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000005516.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000005516.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000005516.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000005516.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000005516.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU910716}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU910716}.
CC -!- SIMILARITY: Belongs to the XK family. {ECO:0000256|ARBA:ARBA00008789,
CC ECO:0000256|RuleBase:RU910716}.
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DR RefSeq; XP_004066625.1; XM_004066577.2.
DR AlphaFoldDB; H2LHQ2; -.
DR Ensembl; ENSORLT00000005517.2; ENSORLP00000005516.1; ENSORLG00000004398.2.
DR GeneID; 101168926; -.
DR KEGG; ola:101168926; -.
DR eggNOG; KOG4790; Eukaryota.
DR GeneTree; ENSGT01070000253766; -.
DR HOGENOM; CLU_028534_1_0_1; -.
DR InParanoid; H2LHQ2; -.
DR OMA; NIWPHEA; -.
DR OrthoDB; 3385375at2759; -.
DR TreeFam; TF316454; -.
DR Proteomes; UP000001038; Chromosome 2.
DR Bgee; ENSORLG00000004398; Expressed in testis and 4 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:1902742; P:apoptotic process involved in development; IBA:GO_Central.
DR GO; GO:0043652; P:engulfment of apoptotic cell; IBA:GO_Central.
DR GO; GO:0070782; P:phosphatidylserine exposure on apoptotic cell surface; IBA:GO_Central.
DR InterPro; IPR018629; XK-rel.
DR PANTHER; PTHR16024; XK-RELATED PROTEIN; 1.
DR PANTHER; PTHR16024:SF9; XK-RELATED PROTEIN 6; 1.
DR Pfam; PF09815; XK-related; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910716};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Transmembrane {ECO:0000256|RuleBase:RU910716};
KW Transmembrane helix {ECO:0000256|RuleBase:RU910716}.
FT TRANSMEM 84..103
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 115..139
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 322..342
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 354..371
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 383..401
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 410..435
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
SQ SEQUENCE 565 AA; 64266 MW; 6465EA59B866B0D7 CRC64;
MAAQSDGGKA AGCGGFAQLY DVDAEEPLDS AAIHICQCCR TSACYWGCRS ACLGSLLGGG
QPVGGIGVRE THCPPREQLW LDCLWIILAL LVFFWDIGTD LCLAVDYYQR QDYLWFGLTL
FFVLVPSVLV QILSFRWFVQ DYTGGGLGDV EGLTKRGTVT LGCLYPGKDR LQLASIWLWQ
ATIHILQLGQ VWRYIRTLYL GLMSRRQKEH QRRWYWAMMF EYADVNMLRL LEAFLESAPQ
LVLQLCIMIQ ENRAETLQCI SSLASLLSLA WVLASYHKLL RDSRDDQRSM SYRGALLHLF
WRLLTISSRV LSLALFASLF HIYFGIFVVL HWCAMAFWVV HGGTDFCMSK WEEVLFNMVV
GIVYIFCWFN VKEGRTRYRM VVYYIIVLAE NTILTGLWYA YRDPVLTDSY AVPALCGVYF
TFIGGVLIML LYYGFLHPAT AHLQPSPASS CCAQLLWGLP LPPSAPPTAP PTPAHMVKSQ
TDEDVAETCL PVFQVRSTPT TSKPEGPLIK IDMPRKRYPA WDAHYVDRRL RRTINILQYI
TPGAVGIRYR DGPLLYELLQ YESSL
//
