ID   H2LNH5_ORYLA            Unreviewed;      1355 AA.
AC   H2LNH5;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 2.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=Disco interacting protein 2 homolog C {ECO:0000313|Ensembl:ENSORLP00000007602.2};
GN   Name=DIP2C {ECO:0000313|Ensembl:ENSORLP00000007602.2};
OS   Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000007602.2, ECO:0000313|Proteomes:UP000001038};
RN   [1] {ECO:0000313|Ensembl:ENSORLP00000007602.2, ECO:0000313|Proteomes:UP000001038}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000007602.2,
RC   ECO:0000313|Proteomes:UP000001038};
RX   PubMed=17554307; DOI=10.1038/nature05846;
RA   Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA   Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA   Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA   Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA   Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA   Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT   "The medaka draft genome and insights into vertebrate genome evolution.";
RL   Nature 447:714-719(2007).
RN   [2] {ECO:0000313|Ensembl:ENSORLP00000007602.2}
RP   IDENTIFICATION.
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000007602.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   STRING; 8090.ENSORLP00000007602; -.
DR   Ensembl; ENSORLT00000007603.2; ENSORLP00000007602.2; ENSORLG00000006045.2.
DR   eggNOG; KOG3628; Eukaryota.
DR   GeneTree; ENSGT00950000182997; -.
DR   HOGENOM; CLU_001345_0_0_1; -.
DR   InParanoid; H2LNH5; -.
DR   TreeFam; TF312871; -.
DR   Proteomes; UP000001038; Chromosome 17.
DR   Bgee; ENSORLG00000006045; Expressed in animal zygote and 13 other cell types or tissues.
DR   CDD; cd05905; Dip2; 2.
DR   Gene3D; 3.30.300.30; -; 2.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   InterPro; IPR037337; Dip2-like_dom.
DR   PANTHER; PTHR22754; DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED; 1.
DR   PANTHER; PTHR22754:SF33; DISCO-INTERACTING PROTEIN 2 HOMOLOG C; 1.
DR   Pfam; PF00501; AMP-binding; 2.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT   DOMAIN          131..439
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          775..1185
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   REGION          21..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..36
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1355 AA;  148392 MW;  A2896EE0284EFEB7 CRC64;
     APPDVTGYTN TTTDGIQVER APVSVTSAQR QTPKYGNAEL MDTGDGVPVS SRVSAKIQQL
     VNTLKRPKRP PLREFFVDDF EELLEVQQPD PNQPKAEGAQ MVAVQGEKLG VVTNWPPSLE
     AALQRWGTIS PKAPCLTTMD TNGKPLYVLT YGKLWSRSVK VAYNLLHKLG TKQEPLVRPG
     DRVALVFPNN DPGAFMTAFY GCLLAEVVPV PIEVPLSRKD AGSQQIGFLL GSCGVTVALT
     SDACHKGLPK SPTGEVQQFR GWPKVLWFVT ESKHLSKPPR DWFPYIKEAT QDTAYIEYKT
     CKDGGVLGVT VTRIAMLTHC QSLTQSCSYT EAETIVNVLD FKKDVGLWHA VQTSVMNMMH
     VISIPYALMK VNPLSWIQKV CLYKAKVACV KSRDMHWALV AHRDQRDVNL SSLRMLVVAD
     GSNPWSISSC DAFLNVFQTK GLKPEVICPC ASSPEALTVA IQRPLEEGST PPGRGILSMQ
     GLSHGVIRVD SEEKLSVLTL QDVGSVMPGG VMCVVKLEGV PQLCKTDEIG ELCVCTVATG
     TSYYGLSGMT KNTFEVFPLA NDGSSISDLP FTRTGLLGFI GPAGLIFVAG KMDGLMVVGG
     RRHNADDIVA TALAVEPMKF VYRGRIAVFS ITVLHDERIV VVAEQRPDST EEDSFQWMSR
     VLQAIDSIHQ VGVYCLALVP SNTLPKTPLG GIHLSETKQL FLEGALHPCN VLMCPHTCVI
     NLPKPRQKQP EIGPASVMVG NLVSGKRIAQ ASGRDLGQIE DNDQARKFLF LSEVLQWRAQ
     TTPDHVLYTL LNSRGTIASS LTCVQLHKRA EKIAAILAER GPLQDGDHIA LVYPPGIDLI
     AAFYGCLYAG CVPITVRPPH PQNISTTLPT VKMIVEVSRS VCVMTTQVIS KLLRSKEASA
     TVDIRTWPPI IDTDDLPKKK PPLLHKPSNA DTLAYLDFSV STTGMLAGVK MSHAATSAFC
     RSIKLQCELY PSREVAICLD PYCGLGFVLW CLCSVYSGHQ SILIPPSELE VNPALWLSAV
     SQYKVRDTFC SYSVMELCTK GLGLQTDSLK SRGLDLSRVR TCVVVAEERP RTALTQSFSK
     LFKDLGLHPR AVSTSFGCRV NLAICLQGTS GPDPTTVYVD MRALRHDRVR LVERGSPHSL
     SLMESGKILP GVRIIIANPE TKGPMGESHL GEIWVHSGHN ASGYFTVYGD EALQSDHFSS
     RLSFGDTQTV WARTGYLGFL RRTELTDASG ERHDALYVVG ALEEAMELRG MRYHPIDIET
     SVIRTHKSIT ECAVFTWTNL LVVVVELDGS EQEALDLVPL VTNVVLEEHY LIVGVVVVVD
     IGVIPINSRG EKQRMHLRDG FLADQLDPIY VAYNM
//