ID H2LPI3_ORYLA Unreviewed; 926 AA.
AC H2LPI3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
GN Name=si:ch211-180a12.2 {ECO:0000313|Ensembl:ENSORLP00000007966.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000007966.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000007966.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000007966.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000007966.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000007966.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2LPI3; -.
DR STRING; 8090.ENSORLP00000007966; -.
DR Ensembl; ENSORLT00000007967.2; ENSORLP00000007966.2; ENSORLG00000006342.2.
DR GeneTree; ENSGT00940000167101; -.
DR HOGENOM; CLU_137120_0_0_1; -.
DR InParanoid; H2LPI3; -.
DR OrthoDB; 4222825at2759; -.
DR Proteomes; UP000001038; Chromosome 19.
DR Bgee; ENSORLG00000006342; Expressed in intestine and 9 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00098; IgC1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR23411:SF44; -; 1.
DR PANTHER; PTHR23411; TAPASIN; 1.
DR Pfam; PF07654; C1-set; 3.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00407; IGc1; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..926
FT /note="Ig-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017258894"
FT TRANSMEM 334..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..120
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 125..218
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 223..313
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 626..727
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 837..874
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 838..857
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 926 AA; 103555 MW; 5B6CDFA81B8D22DB CRC64;
MQCKVLIFVV LLALIKHVSL AEFEASPNTN ITFPCNVSLN EDQRDVSLMK VKWIRNGSDV
ASFGETATMI QNGFRWDNKT FINGDFSITL LKASLTLQGV YECTVIYNSS SIHTSNVTFS
ITAPPSLTVP QRWVVLGKKA QIECHARGYY PPPISFSWTR NGKEIKPLYQ VEGEQSSDGY
YAATANLAYY PSQEDRNATF VCKVLHRSSY QERDFQLNIT FVPTVKLSVM SSASNKDPLT
LYCDVGRFYP ETVSVSWFQN GTALPDPPAV DQNPDGTYKT RHFFTLSPEQ RQQRGPVKCA
VTLPGVENSV NVSEDLEKLD PQNETAAMNK SAKALVSMMC ISIVLVFLLC FGFSWRRRDE
KQKSLTVSGI ILPPRVIVGQ KGRVSISIEG RRVDRVQTVW FLNDTPISDT SLIGTSMSNF
NCLYTPLTTV HLPYGLTLTS PASEKGPLLT SRGKMGYYKL HTQGPLHSSR SGTQQLISAL
TFIPQISLHK GAVFKCQVSY IGKDKIVQER VSEKFTILSP PEVSEIQLTE TQNDSDVISM
KVSASHFHPD VITFRWFCQG GELSPVASEA SSSPRPNAEG LFSAYSQCKL PRGELEKGAT
KVWVKVHHIA LKHPIARESR GFIKRPCVSE IISSDVSSSQ TATLGCEITD FYPPNVSVTW
LSLRGGEEDD REEEVIEGGE LWGPIQIQSR RFRATASLER RLIHQEKERR GGIICRVDHC
SLSEPIEKHW RYGGNVPPHI PSSISVCWSG EGVGVFSILL KGGHPKPKLL WTVGGPTFLP
LVSSETEEIG DDGMRELKSV CALERSTTLS DPANQQLKKR RKGHQIKTKV AVADPDTKGI
EYIDEREDEK NPDKDEETIS EEYEESDTEK EDDPNALHIN RVNLMKDPKE KMKVRLQVCL
EITHPALKLP VYRHWTEPYE EISPSA
//
