ID H2LZJ7_ORYLA Unreviewed; 622 AA.
AC H2LZJ7;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=Plastin-3 {ECO:0000256|ARBA:ARBA00039437};
DE AltName: Full=T-plastin {ECO:0000256|ARBA:ARBA00041485};
GN Name=LOC101161915 {ECO:0000313|Ensembl:ENSORLP00000011569.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000011569.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000011569.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000011569.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000011569.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000011569.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR RefSeq; XP_004076549.1; XM_004076501.2.
DR RefSeq; XP_011481938.1; XM_011483636.1.
DR AlphaFoldDB; H2LZJ7; -.
DR STRING; 8090.ENSORLP00000011569; -.
DR Ensembl; ENSORLT00000011570.2; ENSORLP00000011569.2; ENSORLG00000009227.2.
DR GeneID; 101161915; -.
DR KEGG; ola:101161915; -.
DR eggNOG; KOG0046; Eukaryota.
DR GeneTree; ENSGT00950000183097; -.
DR HOGENOM; CLU_015284_2_0_1; -.
DR InParanoid; H2LZJ7; -.
DR OrthoDB; 5475188at2759; -.
DR TreeFam; TF300680; -.
DR Proteomes; UP000001038; Chromosome 14.
DR Bgee; ENSORLG00000009227; Expressed in gastrula and 14 other cell types or tissues.
DR GO; GO:0005884; C:actin filament; IBA:GO_Central.
DR GO; GO:0032432; C:actin filament bundle; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0051017; P:actin filament bundle assembly; IBA:GO_Central.
DR GO; GO:0051639; P:actin filament network formation; IBA:GO_Central.
DR CDD; cd21292; CH_PLS_rpt1; 1.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 4.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR039959; Fimbrin/Plastin.
DR InterPro; IPR001751; S100/CaBP7/8-like_CS.
DR PANTHER; PTHR19961; FIMBRIN/PLASTIN; 1.
DR PANTHER; PTHR19961:SF32; PLASTIN-3; 1.
DR Pfam; PF00307; CH; 4.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00033; CH; 4.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 2.
DR PROSITE; PS50021; CH; 4.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS00303; S100_CABP; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 8..43
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 48..79
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 115..231
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 259..370
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 389..498
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 510..619
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
SQ SEQUENCE 622 AA; 69791 MW; 63EA3243D42599DB CRC64;
MSARITKEEE EEMREIFGKI DLDSNGFISD YELSELLKEA GHPLPGYRVR EILQELDRNK
DNQISFDEFL AIVKELRGSQ VAKTFRKAIN RKEGILAIGG TSELSSVGTQ HSFSEEERFA
FVNWINTALE KDPDCQHVLP MNPNTDSLFT SVGDGIVLCK MINLSAPDTI DERTINKKKL
TPFTIQENLN LALNSASAIG CHVVNIGALD LKEGKPHLVL GLLWQIIKIG LFADIELSRN
EALAALLRDG ETLEDLMKLS PEELLLRWAN YHLENAGYKK INNFSSDIKD SKAYFHLLNQ
ISPKGKDEGQ PCIDINMAGF NEKDDLKRAE AMLQQADRLG CRQFVTPTDV VNGNPKLNLA
FVANLFNKYP ALTKPENQDI DWGLLEGETR EERTFRNWMN SLGVNPHVNH LYGDLQDALV
ILQLYEKIKI PVDWNNKVNK PPYPKLGTNM KKLENCNYAV ELGRSAKFSL VGIGGQDLND
GNPTLTLAVV WQLMRRYTLN VLEDLGDGDK VNDDIIVKWV NKTLADAEKS TKISSFKDKE
ISTSLSVLEL IDAIQPGSVN YELIKTSSLS DADKLENAKY AISMARKIGA RVYALPEDLV
EVKPKMVMTV FACLMGRGMK RV
//
