GenomeNet

Database: UniProt
Entry: H2M5P9_ORYLA
LinkDB: H2M5P9_ORYLA
Original site: H2M5P9_ORYLA 
ID   H2M5P9_ORYLA            Unreviewed;      2835 AA.
AC   H2M5P9;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 2.
DT   10-FEB-2021, entry version 45.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSORLP00000013781};
GN   Name=cenpf {ECO:0000313|Ensembl:ENSORLP00000013781};
OS   Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000013781, ECO:0000313|Proteomes:UP000001038};
RN   [1] {ECO:0000313|Ensembl:ENSORLP00000013781, ECO:0000313|Proteomes:UP000001038}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000013781,
RC   ECO:0000313|Proteomes:UP000001038};
RX   PubMed=17554307; DOI=10.1038/nature05846;
RA   Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA   Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA   Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA   Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA   Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA   Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT   "The medaka draft genome and insights into vertebrate genome evolution.";
RL   Nature 447:714-719(2007).
RN   [2] {ECO:0000313|Ensembl:ENSORLP00000013781}
RP   IDENTIFICATION.
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000013781};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSORLP00000037086}
RP   IDENTIFICATION.
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000037086};
RG   Ensembl;
RL   Submitted (OCT-2018) to UniProtKB.
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DR   RefSeq; XP_011490649.1; XM_011492347.1.
DR   STRING; 8090.ENSORLP00000013781; -.
DR   Ensembl; ENSORLT00000013782; ENSORLP00000013781; ENSORLG00000010987.
DR   Ensembl; ENSORLT00000034980; ENSORLP00000037086; ENSORLG00000010987.
DR   GeneID; 101167860; -.
DR   KEGG; ola:101167860; -.
DR   CTD; 1063; -.
DR   eggNOG; ENOG502QVMD; Eukaryota.
DR   GeneTree; ENSGT00730000111187; -.
DR   HOGENOM; CLU_317336_0_0_1; -.
DR   InParanoid; H2M5P9; -.
DR   OrthoDB; 205405at2759; -.
DR   Proteomes; UP000001038; Chromosome 3.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 1.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT   DOMAIN          1..306
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1811..1953
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2049..2190
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2743..2785
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          122..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          255..281
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          502..524
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1064..1085
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1564..1667
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2189..2224
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2526..2557
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2653..2714
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2731..2752
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2781..2835
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          20..82
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          162..196
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          620..672
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          687..714
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          719..767
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          793..838
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          846..968
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1095..1122
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1130..1216
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1220..1363
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1371..1461
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1487..1535
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1689..1758
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1766..1800
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1815..1849
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1857..1884
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1892..1912
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1920..1961
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2316..2357
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2365..2504
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        127..155
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        258..281
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1592..1612
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1613..1650
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1651..1667
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2526..2544
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2654..2670
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2671..2693
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2801..2826
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2835 AA;  326244 MW;  98C0CB13E4C5ADAF CRC64;
     MSWAVEEWKD GLPGKALQKI QEMEVQLDKL KKERTQKQFQ LDSLEAALQK QKQKVDSERT
     EISALKRENQ SLVESCDAVE KARQKTVHDL GIKEQQVSYL EGQLSSCKKT IDRLEQELKK
     YKNELDRSQP ANSSTLSSSS SELHSYNTPQ KSFATPAPVS AFKHQDNRLE ELQEKYNQEV
     EERKRLETEL KVLQVKLLSQ SSVTVSHKDI AARQAGSSIF PWQQQDQVHS RQSLDMKETP
     LKRRGTSLWD AHEETPIKSS QHMNSSRTFQ SPSGSSHQME QLKTLNQELH GRVSELERNL
     SNQEKEIRTQ AFKLQELQTQ LSKAHKDLAE RERDLVKASQ ELNQATDRHQ QLEAKYSSVE
     QKMKQVTEEL SCQRHNAESC KQMLEQKLKD QERNSQKDLA QLQSSHQALD QELNQTRTKL
     TQAVQQSKKD YNILEADMEK MRFQKSQLEK EMEEQKLKLL RSEQSLQASQ TKELDLRKKM
     EELQKEKNTL TVQLDQSDRR LSQLEEEKKT SEQSLKRTQG LLNDIKAKSE GQTEELKRLQ
     AKLQQQTQTS ERELEHLKKT LSDAESKHEK AQIELQKQKQ ELEMLCNKVS IFESESYKLK
     SNLAVSQNEC KTLKEEHQAV LEWKTAKEKL INETEALQKN LKDQINSLES DLSSVNEANA
     ELQKKLVVTE EEKGTLSAHI DSLKGELLNK CTELEEREHQ YKELQNQLSA AGLKHTKDLE
     NIGVQVTQLE AQITELESRL HKETARAELA EKTKAELQEE HQAACDLVHS KEQLVELGQA
     ENTQLKESLG RVTAQLEEQN SSFAEERAAL LKQCEESVSA KAEENERIKL ETEEAKQELL
     LCKSQVTSME QLLKVQEQLR AELQKEIKTT SEAEGDLKKM YEKQSEELTQ LEKELKNQLS
     HTEEKEKQLR ASEAQVESAE KLRDELEKTV QKMMEEAEVL QQSHTVKLNA LQQQISSLEE
     EVATNKDAAE EVPLLKNKLD LANRSIADLK TSIEDLKNNL FSANNNAANL NSTLAEKMDL
     ILTLEKEIND LADRMREESK KHTQEMEVAL DKEKDLKEQL ETSRKSLATA KAESNSRRDE
     IKTMKTTLSA ASDGLKERDA MIKSLQEKLD KAETEQAKTS DLLKEKIVSM NKITVQLEML
     QMDLEDNENA MNSVEELKET IASMEAQLAH NQSQMSEMEA RLEESKAQVS VLETRLDEVQ
     SEVSLLETKY VTAKEELFER SCEISRLEEE ANRREQLEEK LVTLESKLNQ AEEEKTKSEM
     AHRQMIQEKE HSLSQVTEEK QNLELLLSCL RDDSKQVETE MILLKEEKKQ LDARVDKLWE
     ENQQLQARVQ ELVGEKQQTE TKIDEMALKA QEAESTLNQV LEEKSHLEVG LNLMNEEKAQ
     IEGKLLALTS EKSDLVSNVN RLQQEKLQLE FSCTQYSEEN GKLQFSLNQA SEEKQQLEDK
     TEKLEEGMAS LREENQRTQH SLLLSSQECQ RLREQIDMKT SEEHERNQRF EAEQAELQQK
     LAALQKELTV FKQQCDSLQE QVDQQHRLIQ QLSESPNPQD PTEVSYHHPM STNMDVISMD
     EAGEQENLEP EPDANVSISP DLHPLNGPSD ASRMRELSQQ SDSVCSVDTG DSEDQLLSRK
     GIPDQEMVQD RVGSEKEEEW DGDVDKISKE DQLPQSQASE ASCSSEDVQT NDSVICDLCE
     TEQLKSPAAE LKNQELHQYQ EIISKQQQEL QALRSELDCL NSDLEVRKEM TSELEIQVQN
     LEKKVGVAEE EARGAAHQLC SALETRNNLS SELTQLSEEK ETLTLQLQTA QSQLTDAMEM
     LQGLDMAKGG WDEKFLQQES ELKRVRSEKA NLEQHILGME AELESMQVES SRRKEEMEAQ
     KRTCSAMEQQ LETLRTETIQ LRSEIVFCTE ERDELTQSVA HWKDQVNCLE KSNCDIRSLI
     SILEDDIRAG KKEYEALQSS MEKLKEEKEQ LVEQVKVMEV AITQQHGEKE ELLGHLNQCK
     EDQTSADQSS ESMVGKIQAL EGEVCRLSQS LESSLLEKGE IASRLNSTQD EVMQMRTGIE
     KLQVRIESDE RKKKKMGELL KAAQRKSDSL QDRIDALERE KEDLEQSLEQ TVLQAETFKA
     ELEEERRQVE EEKEELSNKL SELSATLDHL MVEKAQMERE LQAKSREIEE LKAAKDELEK
     GLEKAEVERT EKESLKNRVD DLERVMREEA EMQNRKIDDL QAQLQTSRHR QEQVEQKSKE
     MNEEKKKMQF LLEEMEKEKR TLQISLEEWQ TDSQRLRSQE EERQKERNNL RADVESLEEE
     IKKLKTSLSV KEEEICALVK EKEAEAEKRQ ASLKSISSLM EEKEQAEKVN LQLVEEKEKL
     QSGLLSLEQE MDNLRCSLIP LGEEKDRLHH EREILTDEKV KLQSDFTSLE KEKWDLEQKL
     TTLKQEKLNT EKDNQTLETE KQELLSSLHL LKEEKNNLSS TCSLLEAEKQ QAQEEKEKLK
     EELESLQKVF ASAERKVETH KQSITKLSEQ VSELTNHAAR LSKERDSALS KMNLWMKTCK
     QLEQEKQKIL SSSGENGSRE DLQGEVTQLR SEAEDRKRQV EELKTVLEKK RTEVEDGLRE
     CREKQRELGE LKADLKAKTE EILEKDRELE KTRAELEELN SLAEEKSREA DECMDKYCNL
     MVKVHKLEET NDSLKTQLEQ MSANQRATEA SSSDNRRRSA RKSSSRHQEE NRNTENVAPS
     TPQATLSGKR GHCDINDKES AQEALHNLTK KIKANAVTTP KPRNDEDEFR PEGLPELVQK
     GFADIPLGEA SPFIIRRTTA RRCSPRLAAR SPLPDGKTLG TVPVQSPSCS LSPDNSKRNQ
     QLPREPQPGD NCHVQ
//
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