ID H2M6N8_ORYLA Unreviewed; 572 AA.
AC H2M6N8;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=ANTXR cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSORLP00000014135.2};
GN Name=ANTXR1 {ECO:0000313|Ensembl:ENSORLP00000014135.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000014135.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000014135.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000014135.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000014135.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000014135.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the ATR family. {ECO:0000256|ARBA:ARBA00008095}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H2M6N8; -.
DR Ensembl; ENSORLT00000014136.2; ENSORLP00000014135.2; ENSORLG00000011277.2.
DR eggNOG; ENOG502QSKR; Eukaryota.
DR GeneTree; ENSGT00940000156522; -.
DR HOGENOM; CLU_029760_0_0_1; -.
DR TreeFam; TF328943; -.
DR Proteomes; UP000001038; Chromosome 9.
DR Bgee; ENSORLG00000011277; Expressed in muscle tissue and 7 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR CDD; cd01474; vWA_ATR; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR008399; Anthrax_toxin_rcpt_C.
DR InterPro; IPR008400; Anthrax_toxin_rcpt_extracel.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR16059; ANTHRAX TOXIN RECEPTOR; 1.
DR PANTHER; PTHR16059:SF11; ANTHRAX TOXIN RECEPTOR 1; 1.
DR Pfam; PF05586; Ant_C; 1.
DR Pfam; PF05587; Anth_Ig; 1.
DR Pfam; PF00092; VWA; 1.
DR PRINTS; PR01217; PRICHEXTENSN.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..572
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017481881"
FT TRANSMEM 301..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 46..234
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 438..572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..489
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..572
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 572 AA; 63245 MW; A809964AB0EF95AD CRC64;
MSPCWRRSFL SLLMFIAMLY ILTAESAGPS SGTRQDKASS CFGGFDLYFV LDKSGSVQNH
WNEIYYFVEH LAHKFTSPQL RMSFIVFSTE GRILMGLTDD REQIRKGLEE LYAVRPGGDT
FMHEGLLRAS EQIYYGNKEG YRTASVIIAL TDGELHENLF HHAERELAKI ADGKDHVFPV
NDGFNALQGA IDSILKKSCI EILAAEPSSI CAGESFQVVV RGNGFLHTRN VNKVLCSFRI
NDTSTKTMKP LIVEDSYLLC PAPVLQDEGM AANLYVSMND GLSFISSSVT ITSLSCSDGT
LLAIALLFLM LLLVLALLWW FWPLCCTVVS SLKEDFDAPK KKWPTVDASY YGGRGVGGIK
RMEVRWGEKG STEEGAKLEK AKNAKVKMPE QEYELSPTRV LNNGMHKPPE PRKWYSPIKS
KLEALWVLLK KGYDRVSIMR PHPGDKGRCM NFTRIKSPPH YPHYNQKPPS IYNPPNRSPP
SPPPNPGSPL SFSFSKLPSL PSTPISSSPS PSAQPPLYTP PPHRALPSPS LQLPCPPAPP
PSPPPCLPPA GTLPPPPGRA PPPLRPPPRP DL
//
