ID H2M753_ORYLA Unreviewed; 337 AA.
AC H2M753;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Transmembrane protein 120Ab {ECO:0000313|Ensembl:ENSORLP00000014304.2};
GN Name=LOC101173961 {ECO:0000313|Ensembl:ENSORLP00000014304.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000014304.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000014304.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000014304.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000014304.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000014304.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Nucleus inner
CC membrane {ECO:0000256|ARBA:ARBA00004473}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004473}.
CC -!- SIMILARITY: Belongs to the TMEM120 family.
CC {ECO:0000256|ARBA:ARBA00009700}.
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DR RefSeq; XP_011481097.1; XM_011482795.1.
DR AlphaFoldDB; H2M753; -.
DR Ensembl; ENSORLT00000014305.2; ENSORLP00000014304.2; ENSORLG00000011423.2.
DR GeneID; 101173961; -.
DR KEGG; ola:101173961; -.
DR eggNOG; KOG4758; Eukaryota.
DR GeneTree; ENSGT00390000007848; -.
DR HOGENOM; CLU_048749_1_1_1; -.
DR InParanoid; H2M753; -.
DR OrthoDB; 314124at2759; -.
DR TreeFam; TF313552; -.
DR Proteomes; UP000001038; Chromosome 13.
DR Bgee; ENSORLG00000011423; Expressed in intestine and 3 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045444; P:fat cell differentiation; IBA:GO_Central.
DR InterPro; IPR012926; TACAN/TMEM120B.
DR PANTHER; PTHR21433; TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA; 1.
DR PANTHER; PTHR21433:SF7; ZGC:103681; 1.
DR Pfam; PF07851; TMPIT; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 130..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 299..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT COILED 5..32
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 337 AA; 40151 MW; 4E9528916570B567 CRC64;
MSEDLAEVVN EWKRLEEEYQ QLQDTHRRYL HKLDEISKLQ NNCSSSIVRQ RKNLKELSRR
TKKKRLSQEE ANTLAEIKDK LKTRQNAFDE MEAFLPKKNG LYLSLVLGNV NVTLFTKQSK
FAYKDEYEKF KLYLTVILLL LSFICYGFVS YRFLDAILNF LLVWFYCTLT IRESILITNG
SRIKGWWVFH HYISAFLSGV MLTWPDGNLY KMFRGQFLAY CLYQSFVQCL QCYYQSGCLY
RLRTLGERHN MDLTVEGFQS WMWKGLTFLL PFLFFGHFWQ LFNGLSLFRM ARLPDCKEWQ
VLVCGLCFLI LFMGNFFTTL AVVHHKSKKR NQNSKSQ
//
