ID H2MC19_ORYLA Unreviewed; 239 AA.
AC H2MC19;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=WxxW domain-containing protein {ECO:0000259|Pfam:PF13330};
GN Name=LOC101160704 {ECO:0000313|Ensembl:ENSORLP00000016097.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000016097.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000016097.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000016097.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000016097.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000016097.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR AlphaFoldDB; H2MC19; -.
DR Ensembl; ENSORLT00000016098.2; ENSORLP00000016097.1; ENSORLG00000012851.2.
DR eggNOG; ENOG502R7BT; Eukaryota.
DR GeneTree; ENSGT00390000008152; -.
DR HOGENOM; CLU_105906_0_0_1; -.
DR OMA; FICRKRD; -.
DR OrthoDB; 5383072at2759; -.
DR Proteomes; UP000001038; Chromosome 24.
DR Bgee; ENSORLG00000012851; Expressed in gastrula and 5 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR InterPro; IPR039675; CILP1/CILP2.
DR InterPro; IPR025155; WxxW_domain.
DR PANTHER; PTHR15031:SF6; C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR15031; CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP; 1.
DR Pfam; PF13330; Mucin2_WxxW; 2.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..239
FT /note="WxxW domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015092198"
FT DOMAIN 56..139
FT /note="WxxW"
FT /evidence="ECO:0000259|Pfam:PF13330"
FT DOMAIN 150..235
FT /note="WxxW"
FT /evidence="ECO:0000259|Pfam:PF13330"
FT REGION 24..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 239 AA; 26818 MW; 12972C6D20BF064D CRC64;
MIKLACIAIV AGLVFVEPKE ENQIHSRSSG FSKRPPPESL PEPELDIYSS VPIQCWTQWF
NSDNPTGDED QETLARLRIQ YPGKICPIPV GIEATNLFGI PADQTGDTIF QSDTTTGFIC
RNGDQISGEC NDYRVRFSCT PPYCADTACW TQWFDRDNPS GTGDWETLQS LRRENPDKIC
EDPWYIEAVT VDSPSTPAIQ TGENFYVFSP TQGLVCRQED QSSKTCLDYK VRFGCPCTK
//
