ID H2MCE1_ORYLA Unreviewed; 333 AA.
AC H2MCE1;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Methyltransferase like 9 {ECO:0000313|Ensembl:ENSORLP00000016226.2};
GN Name=mettl9 {ECO:0000313|Ensembl:ENSORLP00000016226.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000016226.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000016226.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000016226.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000016226.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000016226.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_004080741.1; XM_004080693.2.
DR AlphaFoldDB; H2MCE1; -.
DR STRING; 8090.ENSORLP00000016226; -.
DR Ensembl; ENSORLT00000016227.2; ENSORLP00000016226.2; ENSORLG00000012946.2.
DR eggNOG; KOG3987; Eukaryota.
DR GeneTree; ENSGT00390000013648; -.
DR HOGENOM; CLU_056100_0_0_1; -.
DR InParanoid; H2MCE1; -.
DR OrthoDB; 8628at2759; -.
DR TreeFam; TF314187; -.
DR Proteomes; UP000001038; Chromosome 19.
DR Bgee; ENSORLG00000012946; Expressed in blastula and 14 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0106370; F:protein-L-histidine N-pros-methyltransferase activity; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR007884; METL9.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12890; DREV PROTEIN; 1.
DR PANTHER; PTHR12890:SF0; PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE; 1.
DR Pfam; PF05219; DREV; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 333 AA; 38115 MW; F804FBBA1EBD0033 CRC64;
MCHLQLKTLF FVAWLLGYVA FLLSIRRMWT AKHARSPLVR SLVLNMVNEH EASGARETHE
WYRCCPDLLG ESVRPLFIQS HLDSDTTDFL NRSAEKSGWL FTQLYHSLVS TVLSPVLSRT
SINGVLGRGS MFVFSSEQFQ QLLRIGPDWT AERLLDLGAG DGGVTEVMGV HFRQVFATEV
SVPMKWHLQR RNYKVLGIDE WQHVGFQYDL ISCLNLLDRC EDPLHLLREI RKALVPKTGR
LVLAAVLPFQ PYVEVGGKWE RPKEHLKVKG KTWEEQVTDL SSEVFPRVGF EVEAVTRLPY
LCEGDMYNDY YVLDDAVFVL KASGDSEQSV HEL
//
