ID H2MCF9_ORYLA Unreviewed; 694 AA.
AC H2MCF9;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Abnormal spindle-like microcephaly-associated protein ASH domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000016245.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000016245.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000016245.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000016245.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000016245.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2MCF9; -.
DR STRING; 8090.ENSORLP00000016245; -.
DR Ensembl; ENSORLT00000016246.2; ENSORLP00000016245.2; ENSORLG00000012964.2.
DR eggNOG; ENOG502QQ4F; Eukaryota.
DR GeneTree; ENSGT00940000163228; -.
DR HOGENOM; CLU_006718_0_0_1; -.
DR InParanoid; H2MCF9; -.
DR TreeFam; TF340616; -.
DR Proteomes; UP000001038; Chromosome 6.
DR Bgee; ENSORLG00000012964; Expressed in testis and 5 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR031549; ASH.
DR InterPro; IPR033305; Hydin-like.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR000535; MSP_dom.
DR InterPro; IPR008962; PapD-like_sf.
DR PANTHER; PTHR23053; DLEC1 DELETED IN LUNG AND ESOPHAGEAL CANCER 1; 1.
DR PANTHER; PTHR23053:SF0; HYDROCEPHALUS-INDUCING PROTEIN HOMOLOG; 1.
DR Pfam; PF15780; ASH; 1.
DR Pfam; PF00635; Motile_Sperm; 1.
DR Pfam; PF14874; PapD-like; 1.
DR SUPFAM; SSF49354; PapD-like; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 179..246
FT /note="MSP"
FT /evidence="ECO:0000259|Pfam:PF00635"
FT DOMAIN 478..577
FT /note="Abnormal spindle-like microcephaly-associated
FT protein ASH"
FT /evidence="ECO:0000259|Pfam:PF15780"
SQ SEQUENCE 694 AA; 77396 MW; 90E63D58A4F3EE05 CRC64;
VQLMLVNLAS PVGPPFALKT VTPSAFIQNM LQSTEERLNN TTEVNPPRIL EWFDMSNTLH
QKFSLIHMER PLFQPFPSEL VFQNFTPLQT YKLPLILLNN DKVLRHVKLE QQESEDFFVV
GPVNSGSKVA PGMSITFTVG FTPKENKDYE GRLICVTERE RFEIPVRAIG PRAILDFRDE
IFFPICLVKA FTQKTHLLRN IGNSQAKFKL HTQRPFSVKP SFGTLDVGES LQVTVSFHPL
TVGDHREDLL LHYHTGEDVF ISLCGSCEEL DIHLEPECVT LKRTYIGLTN VHTVSLTNSS
DTTLQYCWTM WPIQEVEEKN SVLLQEEKEE ESKGQRLFEC ESSSTAAHHY SVQSGALQEN
GTTINCFYIF VVQKGEIWPN TTAQFSIVFK PEEAKIYQHT VYCDVTGRES NLPLTITGEG
LGPELELSYS LMDMNNVFIG DKDQYDVQMS NVGFIEALFR FSVPDTTFGR CFSISPVEGV
VPPGASQNVK VTFQSSNLGT FSEDLLLNVN GQPHPHTLTF RGCVIGPTFH FNVFELNFGD
VAFGFPATLT CTLFNTSFVP MNFSLRVLGD GSGSQSVSSS SQVSNLSHKN WKGHAARVRP
VEFTIIPAAG SVRAMSDVNI KVTLCSNTVK VYRLALVVDV EGGQTLQNLC DPALSSEAVS
REGVSFLHSQ ASIDADSLRI TLHLPDKEPH QSNS
//
