ID H2MDH5_ORYLA Unreviewed; 154 AA.
AC H2MDH5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Hydroxyacyl-thioester dehydratase type 2 {ECO:0000313|Ensembl:ENSORLP00000016620.2};
GN Name=HTD2 {ECO:0000313|Ensembl:ENSORLP00000016620.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000016620.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000016620.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000016620.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000016620.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000016620.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2MDH5; -.
DR STRING; 8090.ENSORLP00000016620; -.
DR Ensembl; ENSORLT00000016621.2; ENSORLP00000016620.2; ENSORLG00000013267.2.
DR eggNOG; KOG1206; Eukaryota.
DR GeneTree; ENSGT00530000065109; -.
DR HOGENOM; CLU_094876_3_4_1; -.
DR InParanoid; H2MDH5; -.
DR TreeFam; TF332521; -.
DR Proteomes; UP000001038; Chromosome 5.
DR Bgee; ENSORLG00000013267; Expressed in mesonephros and 14 other cell types or tissues.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0019171; F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity; IBA:GO_Central.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IBA:GO_Central.
DR CDD; cd03449; R_hydratase; 1.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR002539; MaoC-like_dom.
DR PANTHER; PTHR43437:SF3; HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43437; HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF01575; MaoC_dehydratas; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 32..130
FT /note="MaoC-like"
FT /evidence="ECO:0000259|Pfam:PF01575"
SQ SEQUENCE 154 AA; 16991 MW; 89EBB7D5FDE682E0 CRC64;
MWRNIIKLGL SSVAAARPHN RLLHVGQRAS LTKTFSFRHV ELFAELTGDT NPLHVDPAYA
STTSFETPIV HGVLINGLIS AVLGTKMPGP GCVFLHQEIR FLAPLYVGEE VLAEAEVFKI
KMSFAFISVR CSAKDKVVME GEVMVMMPVE QHKS
//
