ID H2MHT3_ORYLA Unreviewed; 167 AA.
AC H2MHT3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Eva-1 homolog Ba (C. elegans) {ECO:0000313|Ensembl:ENSORLP00000018201.3};
GN Name=eva1ba {ECO:0000313|Ensembl:ENSORLP00000018201.3};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000018201.3, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000018201.3, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000018201.3,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000018201.3}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000018201.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the EVA1 family.
CC {ECO:0000256|ARBA:ARBA00006023}.
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DR RefSeq; XP_004078341.1; XM_004078293.2.
DR RefSeq; XP_011483946.1; XM_011485644.1.
DR AlphaFoldDB; H2MHT3; -.
DR STRING; 8090.ENSORLP00000018201; -.
DR Ensembl; ENSORLT00000018202.3; ENSORLP00000018201.3; ENSORLG00000014522.3.
DR GeneID; 101173006; -.
DR KEGG; ola:101173006; -.
DR CTD; 100004969; -.
DR eggNOG; ENOG502RYRK; Eukaryota.
DR GeneTree; ENSGT00940000154096; -.
DR HOGENOM; CLU_104871_1_0_1; -.
DR InParanoid; H2MHT3; -.
DR OrthoDB; 5359115at2759; -.
DR TreeFam; TF352986; -.
DR Proteomes; UP000001038; Chromosome 16.
DR Bgee; ENSORLG00000014522; Expressed in liver and 13 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR039500; EVA1_dom.
DR PANTHER; PTHR48334:SF2; PROTEIN EVA-1 HOMOLOG B; 1.
DR PANTHER; PTHR48334; PROTEIN EVA-1 HOMOLOG B-RELATED; 1.
DR Pfam; PF14851; FAM176; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..165
FT /note="EVA1"
FT /evidence="ECO:0000259|Pfam:PF14851"
FT REGION 62..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..93
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 167 AA; 18666 MW; 6BF71D06D2D9A389 CRC64;
MDVKKKEMDL LSNSIAALAH IRDNPESFGL YFVLGVCFGL VLTLCLLVIQ ISCKPRTNIS
PSALEKKPLK IPNEDEEESD DEEEEEEEGD ELEAQIPLPS TEIPVGNHVG QQSTDGSLSV
NVFTSAEELE RAQRLEERER IIREIWRNGQ PDILGSGTGT IGRVHYY
//
