ID H2MMF6_ORYLA Unreviewed; 404 AA.
AC H2MMF6;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Serpin domain-containing protein {ECO:0000259|SMART:SM00093};
GN Name=LOC101158815 {ECO:0000313|Ensembl:ENSORLP00000019898.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000019898.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000019898.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000019898.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000019898.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000019898.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the serpin family.
CC {ECO:0000256|RuleBase:RU000411}.
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DR RefSeq; XP_011490048.1; XM_011491746.1.
DR AlphaFoldDB; H2MMF6; -.
DR STRING; 8090.ENSORLP00000019898; -.
DR Ensembl; ENSORLT00000019899.2; ENSORLP00000019898.2; ENSORLG00000015892.2.
DR GeneID; 101158815; -.
DR KEGG; ola:101158815; -.
DR eggNOG; KOG2392; Eukaryota.
DR GeneTree; ENSGT00940000160877; -.
DR HOGENOM; CLU_023330_2_1_1; -.
DR InParanoid; H2MMF6; -.
DR OrthoDB; 3218836at2759; -.
DR TreeFam; TF343201; -.
DR Proteomes; UP000001038; Chromosome 24.
DR Bgee; ENSORLG00000015892; Expressed in sexually immature organism and 10 other cell types or tissues.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:GO_Central.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR Gene3D; 2.10.310.10; Serpins superfamily; 1.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461:SF363; SERINE (OR CYSTEINE) PROTEINASE INHIBITOR, CLADE A (ALPHA-1 ANTIPROTEINASE, ANTITRYPSIN), MEMBER 1, LIKE PRECURSOR-RELATED; 1.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR Pfam; PF00079; Serpin; 1.
DR PRINTS; PR00780; LEUSERPINII.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..404
FT /note="Serpin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017417382"
FT DOMAIN 46..401
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 404 AA; 45061 MW; 224E033F1B5D4FF2 CRC64;
MRGLFLSCAL TALLLAAAWA DHHHGHSHDG ELTCHKLAPP NADFAFALYK NFNAKTAAGQ
NIFFSSLGIA TALSMLSTGA RGDTHSQLFS TLGYSAFSQE QVNEAYEHLF HMLGHSQQDQ
QLDVGNTAAV RSGFTPLESF LKGIKKHFSG EVFNVDFSKP QEATAELNKH IASKTNDKIK
DMVKDLDPET AMVLINYVYF RGQWEKPFDA NLTTKADFYV DENTKVEVDM MKKTGRFDHY
DDNENHTTVV VLPYKGNTSM MILLPNEGKM KQMEDFIDKD KIWHWHNSLF KNNVNFYMPK
FSISVPTSLD DTLKEMGVTN AFGDKADFSG MSSEVMLKLS RASHQAVLSV DETGTEAAAG
TTMEIMPMSM PETVMLNRPF VVLILEHSTR SVLFMGKINN PAAV
//
