ID H2MP96_ORYLA Unreviewed; 798 AA.
AC H2MP96;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Dynein, axonemal, heavy chain 9 {ECO:0008006|Google:ProtNLM};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000020554.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000020554.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000020554.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000020554.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000020554.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2MP96; -.
DR STRING; 8090.ENSORLP00000020554; -.
DR Ensembl; ENSORLT00000020555.2; ENSORLP00000020554.2; ENSORLG00000016407.2.
DR eggNOG; KOG3595; Eukaryota.
DR GeneTree; ENSGT00940000154076; -.
DR HOGENOM; CLU_000038_4_0_1; -.
DR InParanoid; H2MP96; -.
DR TreeFam; TF316836; -.
DR Proteomes; UP000001038; Chromosome 9.
DR Bgee; ENSORLG00000016407; Expressed in testis and 4 other cell types or tissues.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45703:SF4; DYNEIN AXONEMAL HEAVY CHAIN 17; 1.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 207..327
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 359..495
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 501..796
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
SQ SEQUENCE 798 AA; 91281 MW; 78D1E489E8CEC1E5 CRC64;
MNDLNKINPM YQFSLKAFSV VFQRAVKKAK PEEEVRQRVL NLTDSITFSV FQYTTRGLFE
CDKLMFVTQL VFQVLRMNNE INPAELDFLL RCPIQPGVTS PVDYLSNQAW GGIKSLCCME
AFRNLDQDVE STPNRWKRMV ESECPERERL PMEWKSKTSL QKLCIMRVLR PDRMSNAIRN
FVEEKLGSKY TMGRSLDFAS SFEESDSATP MFFILSPGVD PLKDVEEHGK KLGFTLDNKN
LHNVSLGQGQ EIVAEQALEV AAKNGHWVIL QNIHLVARWL KTLEKLVEQH AEQSHENFRV
FFSAEPSATP ETHIIPHGIL ENSIKVTNEP PTGMNANLHK ALDNFSQVSL EACTQENEFK
SIWFALCYFH AVVAGRSKFG PQGWNRPYPF NIGDLTISVN VLQNYLEANR KVPYEDLRYL
FGEIMYGGHI TDDWDRRLCC SYLEEFIKPE MMEGKVFLAP KFPLPGNMQY EGYHKYIDDN
LPGESPYLYG LHPNAEIGFL TQTSEKLFST VLEMQPRDEA VGEEGGMTRE EKVCAVMEEI
TGRLPDQFNM SELFAKAQER SPYEVVALQE CERMNFLIRE IRSSLRELSL GLKGELTMTS
DMESLQNALF LDAVPDGWTK LAYPSTLSLA LWFSDLLTRI SQLEAWSVSF CLPPVVWLSG
FFNPQSFLTA IMQDIARRNK LPLDSMRLQC EVTKRNLEHF SSPPREGAYI HGLFMEGAQW
DTQKGIIVPA GMKELTSPMP VMYIKAVPAS KQDTKDVYRC PVYKTHQRGP TYVWTFDLKS
KEKPSTWTIA GVALILQV
//
