ID H2MS33_ORYLA Unreviewed; 471 AA.
AC H2MS33;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 84.
DE RecName: Full=Tripartite motif containing 35-12 {ECO:0008006|Google:ProtNLM};
GN Name=LOC101168454 {ECO:0000313|Ensembl:ENSORLP00000021567.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000021567.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000021567.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000021567.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000021567.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000021567.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_004069392.1; XM_004069344.2.
DR AlphaFoldDB; H2MS33; -.
DR STRING; 8090.ENSORLP00000021567; -.
DR Ensembl; ENSORLT00000021568.2; ENSORLP00000021567.2; ENSORLG00000017236.2.
DR GeneID; 101168454; -.
DR KEGG; ola:101168454; -.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00970000193381; -.
DR HOGENOM; CLU_013137_0_3_1; -.
DR InParanoid; H2MS33; -.
DR OrthoDB; 5479648at2759; -.
DR TreeFam; TF334286; -.
DR Proteomes; UP000001038; Chromosome 5.
DR Bgee; ENSORLG00000017236; Expressed in animal zygote and 9 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF611; E3 UBIQUITIN-PROTEIN LIGASE TRIM39-RELATED; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 11..51
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 78..119
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 268..455
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 451..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 206..233
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 471 AA; 53286 MW; 4711B4A1C9F99946 CRC64;
MAPGLEEELT CPVCRDIFEE PVFLPCSHSF CRACLKRWWK KKQVLKCPVC NNACGSKRPP
CNLALKNACE AFLLERAEPE PLCRLHAESL KLFCLDHQEP VCLICRDSDA HRNHSFRPVS
EAALDLREEL RRSLEPLQDR LKLLQQVKGH FGHTTEHVLL QTRQAETQMK KQFQELHRFL
QEEEDARIDA LREEERQKVW VLSHETEALR REMAALSDVI QAAEEQLRAA DASFIRNHKA
AVERVQRCRL QDVPRLLSGA LMDVAKHVGN LSFRVWTKMK EVVSYRPVIL DPNTAEAGLL
LSEDLTSVRH GPRQELPENP ERFECHGMVL GSQGFCSGAH SWSVEVGDSR AWLVGVAAEG
FRRKGAPDPS SGLWAVAFSN GEYVSISPTG PSPLHPERKL KSVSVHLDWG RGRLTFTDAE
TQAHIQEFTP GHTEALFPLF HTSSDLPLRI SQAPSGEDED EDCVVRLDDE I
//
