ID H2MTZ9_ORYLA Unreviewed; 825 AA.
AC H2MTZ9;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 3 {ECO:0000256|ARBA:ARBA00020976};
DE AltName: Full=Component of oligomeric Golgi complex 3 {ECO:0000256|ARBA:ARBA00031339};
GN Name=cog3 {ECO:0000313|Ensembl:ENSORLP00000022258.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000022258.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000022258.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000022258.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000022258.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000022258.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Involved in ER-Golgi transport.
CC {ECO:0000256|ARBA:ARBA00002090}.
CC -!- SIMILARITY: Belongs to the COG3 family.
CC {ECO:0000256|ARBA:ARBA00009936}.
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DR AlphaFoldDB; H2MTZ9; -.
DR STRING; 8090.ENSORLP00000022258; -.
DR Ensembl; ENSORLT00000022259.2; ENSORLP00000022258.2; ENSORLG00000017780.2.
DR eggNOG; KOG2604; Eukaryota.
DR GeneTree; ENSGT00390000015682; -.
DR HOGENOM; CLU_011639_1_1_1; -.
DR InParanoid; H2MTZ9; -.
DR OrthoDB; 52120at2759; -.
DR TreeFam; TF314200; -.
DR Proteomes; UP000001038; Chromosome 21.
DR Bgee; ENSORLG00000017780; Expressed in animal zygote and 14 other cell types or tissues.
DR GO; GO:0005801; C:cis-Golgi network; IEA:InterPro.
DR GO; GO:0017119; C:Golgi transport complex; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007030; P:Golgi organization; IBA:GO_Central.
DR GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR InterPro; IPR048685; COG3_C.
DR InterPro; IPR048320; COG3_N.
DR InterPro; IPR007265; COG_su3.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR PANTHER; PTHR13302; CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3; 1.
DR PANTHER; PTHR13302:SF8; CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3; 1.
DR Pfam; PF20671; COG3_C; 1.
DR Pfam; PF04136; COG3_N; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 129..270
FT /note="Conserved oligomeric Golgi complex subunit 3 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF04136"
FT DOMAIN 292..638
FT /note="Conserved oligomeric Golgi complex subunit 3 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF20671"
SQ SEQUENCE 825 AA; 94424 MW; 91E02115F53EEF11 CRC64;
MASTDQSLLD LTDKETREKL SLWDRRTDPT APLTEKQMDS VLEIRTAAET LSVPSELPIE
DLCSLSSRSL QSPFTAPVPG STEDVLLKGF QMLEMENDRI ETAQQFFAWF AKLQANMDQD
ESAKYKKTRD ELNCYQEHCD AILKDVNEAL EYLDSLQKQY LFVSNKTGAL HEACEQLLKE
QSELVELAEN IQQKLSYFNE LENINTKLNS PTLSVNSEGF IPMLSKLDDC IEYVSSHPSF
KDYPVYLAKF KQCLSKAMHL MKVYIVNTMQ SLTSQLTKRD PMGLTNADNA FTLYYVKFRA
AAPKVRSLIE QVEQRSEKIT EYSQLLDEIH QCYLTQREQL LSPCITSTIT DLTNQNSKDH
CALVRSGCAF MVHVCQDEHQ LYNDFFSKPT SKLDELLEKL CLSLYDVLRP LIIHIVHLET
LSELCGILKN EMLEDHVRNN ASQLGAFDTM VKQMLEDVQE RLVYRTHIYI QTDIIGYNPA
PGDLAYPEKL EMMEKISQSL KEEQMKQMSQ ESSFSDVQLE DGGVRRNNSA GSLEVSRLQT
SISPADLHGM WYPTVRRTLV CLSKLYRCID RAVFQGLSQE ALSACIQSLL KASEIIIKSK
TQVDGQLFLI KHLLIMREQI APFHTDFAIK EISLDLKKTR DAAFKILNPK AVPKFFRLNS
HNAILEFLLE GTPEIKEHYI DSKKDVDRHL KFSCEQFIQQ QTQIFVGNLE EFLTKVAALK
KMATEGGPTY NLSQQPWAQP AKINDIVMAT YRVMKSKLPS TLQSLSLYLA NRDTEFILFK
PVRNNIQQVF QRLHALLQEE YSGEDLQIIA CPSMEQINLL LSVNK
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