ID H2MWK7_ORYLA Unreviewed; 424 AA.
AC H2MWK7;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Zinc finger CCCH domain-containing protein 15 {ECO:0000256|ARBA:ARBA00015073};
GN Name=zc3h15 {ECO:0000313|Ensembl:ENSORLP00000023256.2};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000023256.2, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000023256.2, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000023256.2,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000023256.2}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000023256.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the ZC3H15/TMA46 family.
CC {ECO:0000256|ARBA:ARBA00010043}.
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DR RefSeq; XP_004084741.1; XM_004084693.2.
DR AlphaFoldDB; H2MWK7; -.
DR STRING; 8090.ENSORLP00000023256; -.
DR Ensembl; ENSORLT00000023257.2; ENSORLP00000023256.2; ENSORLG00000018606.2.
DR GeneID; 101172631; -.
DR KEGG; ola:101172631; -.
DR CTD; 55854; -.
DR eggNOG; KOG1763; Eukaryota.
DR GeneTree; ENSGT00390000015818; -.
DR HOGENOM; CLU_042870_3_0_1; -.
DR InParanoid; H2MWK7; -.
DR OrthoDB; 5484722at2759; -.
DR TreeFam; TF300892; -.
DR Proteomes; UP000001038; Chromosome 15.
DR Bgee; ENSORLG00000018606; Expressed in blastula and 14 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR Gene3D; 6.20.400.10; -; 1.
DR Gene3D; 4.10.1000.10; Zinc finger, CCCH-type; 1.
DR InterPro; IPR032378; ZC3H15/TMA46_C.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR12681:SF0; ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15; 1.
DR PANTHER; PTHR12681; ZINC FINGER-CONTAINING PROTEIN P48ZNF; 1.
DR Pfam; PF16543; DFRP_C; 1.
DR Pfam; PF00642; zf-CCCH; 1.
DR Pfam; PF14608; zf-CCCH_2; 1.
DR SMART; SM00356; ZnF_C3H1; 2.
DR SUPFAM; SSF90229; CCCH zinc finger; 1.
DR PROSITE; PS50103; ZF_C3H1; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 96..123
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 171..209
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT ZN_FING 96..123
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 171..209
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 53..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 295..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 215..277
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 297..327
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..424
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 424 AA; 48025 MW; DDFE138EFC4E2568 CRC64;
MPPKKPTQAA GTKKTQEKKK EKIIEDKTFG LKNKKGAKQQ KFIKNVTQQV KYGQQSARQV
ENEKGGKKAD KKKELDELNE LFKPVVAAQK VSKGVDPKSV LCAFFKQGQC TKGDKCKFSH
DLSMERKCEK RSVYVDERDE DLEKDTMENW DQKKLQEVVD KKHGEAEKKK AKTQIVCKYF
LDAIENNKYG WFWVCPANGD TCMYRHALPP GFVLKKDKKK EEKEEEISLE ELIENERAAL
GPNVTRITLE SFLAWKKRKR QEKVDKAREE MEKKKADFKA GKSLVVSGRE VFEFHPELVD
DDDDEADDTR YANEESSEEE EEIEAANVQD IDLSRFVPQE VDHTGITVAS TDRFSRDHRG
GTDASGQELM NGACGGAEAN GLPGAQEGGE DGGGEEDVPV DENLFTGEDL EELDEELNTL
ELED
//
