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Database: UniProt
Entry: H2MX40_ORYLA
LinkDB: H2MX40_ORYLA
Original site: H2MX40_ORYLA 
ID   H2MX40_ORYLA            Unreviewed;       348 AA.
AC   H2MX40;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 2.
DT   03-JUL-2019, entry version 43.
DE   SubName: Full=Tubulin folding cofactor C {ECO:0000313|Ensembl:ENSORLP00000023481};
OS   Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae;
OC   Oryziinae; Oryzias.
OX   NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000023481, ECO:0000313|Proteomes:UP000001038};
RN   [1] {ECO:0000313|Ensembl:ENSORLP00000023481}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000023481};
RX   PubMed=17554307; DOI=10.1038/nature05846;
RA   Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B.,
RA   Yamada T., Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D.,
RA   Shimada A., Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A.,
RA   Asakawa S., Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K.,
RA   Sugano S., Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F.,
RA   Nomoto H., Nogata K., Morishita T., Endo T., Shin-I T., Takeda H.,
RA   Morishita S., Kohara Y.;
RT   "The medaka draft genome and insights into vertebrate genome
RT   evolution.";
RL   Nature 447:714-719(2007).
RN   [2] {ECO:0000313|Ensembl:ENSORLP00000023481}
RP   IDENTIFICATION.
RC   STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000023481}, HNI
RC   {ECO:0000313|Ensembl:ENSORLP00000023481}, and HSOK
RC   {ECO:0000313|Ensembl:ENSORLP00000023481};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSORLP00000023481}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HNI {ECO:0000313|Ensembl:ENSORLP00000023481}, and HSOK
RC   {ECO:0000313|Ensembl:ENSORLP00000023481};
RA   Ichikawa K., Yoshimura J., Morishita S.;
RT   "CpG methylation of centromeres and impact of large insertions on
RT   vertebrate speciation.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
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DR   STRING; 8090.ENSORLP00000023481; -.
DR   Ensembl; ENSORLT00000023482; ENSORLP00000023481; ENSORLG00000018800.
DR   eggNOG; KOG2512; Eukaryota.
DR   eggNOG; ENOG410Y28B; LUCA.
DR   GeneTree; ENSGT00940000162058; -.
DR   InParanoid; H2MX40; -.
DR   OMA; CQQLRLH; -.
DR   TreeFam; TF105832; -.
DR   Proteomes; UP000001038; Chromosome 19.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0015631; F:tubulin binding; IEA:InterPro.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR   GO; GO:0007023; P:post-chaperonin tubulin folding pathway; IEA:InterPro.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   GO; GO:0007021; P:tubulin complex assembly; IBA:GO_Central.
DR   Gene3D; 1.20.58.1250; -; 1.
DR   Gene3D; 2.160.20.70; -; 1.
DR   InterPro; IPR017901; C-CAP_CF_C-like.
DR   InterPro; IPR016098; CAP/MinC_C.
DR   InterPro; IPR006599; CARP_motif.
DR   InterPro; IPR027684; TBCC.
DR   InterPro; IPR031925; TBCC_N.
DR   InterPro; IPR038397; TBCC_N_sf.
DR   InterPro; IPR012945; Tubulin-bd_cofactor_C_dom.
DR   PANTHER; PTHR15139; PTHR15139; 1.
DR   Pfam; PF07986; TBCC; 1.
DR   Pfam; PF16752; TBCC_N; 1.
DR   PIRSF; PIRSF037947; Protein_XRP2_; 1.
DR   SMART; SM00673; CARP; 2.
DR   PROSITE; PS51329; C_CAP_COFACTOR_C; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001038};
KW   GTP-binding {ECO:0000256|PIRSR:PIRSR037947-1};
KW   Nucleotide-binding {ECO:0000256|PIRSR:PIRSR037947-1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT   DOMAIN      168    324       C-CAP/cofactor C-like.
FT                                {ECO:0000259|PROSITE:PS51329}.
FT   NP_BIND     260    263       GTP. {ECO:0000256|PIRSR:PIRSR037947-1}.
FT   REGION       36     58       Disordered. {ECO:0000256|MobiDB-lite:
FT                                H2MX40}.
FT   REGION      156    175       Disordered. {ECO:0000256|MobiDB-lite:
FT                                H2MX40}.
FT   COILED      120    140       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   348 AA;  39002 MW;  3FDC4188EA2CFB8F CRC64;
     MLHRLIGNSK LSLGVRENCV QGDFNASKVH ERLEKRHQAR FEDTERRKEA KESQSVSEEK
     SEYFSSTFYS QKAGIDELLS GCAGADRAVV TQKLEEATNK TLQLQKFLND SMLFLTQYEL
     MKAQGALQKL QTTIAEIREE ALPKKKFTFR ARTKAADRGP ATAQHAPPAD TGVTKVDGAP
     PSDLCGFSNM SNEVLIKTAE ELQSRDVLLS HLTNCKVRLF GSPSTVHLKH ISSCEILCGP
     VSTSVFVDHC SSSTLAFACQ QLRTHNATDT QVYLHVTSRA IIEDCSGLSF APFSWTYPTM
     EQDFTVSGLD RNRNNWNQVD DFNWLAAGTH SPNWTVIPEE ERKTTWYL
//
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