ID H2N5A3_PONAB Unreviewed; 742 AA.
AC H2N5A3; A0A2J8VH66; A0A663DH66;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=FCRL3 isoform 4 {ECO:0000313|EMBL:PNJ56849.1};
DE SubName: Full=Fc receptor like 3 {ECO:0000313|Ensembl:ENSPPYP00000000799.1};
GN Name=FCRL3 {ECO:0000313|Ensembl:ENSPPYP00000000799.1};
GN ORFNames=CR201_G0019245 {ECO:0000313|EMBL:PNJ56849.1};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000000799.1, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000000799.1, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PNJ56849.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Susie {ECO:0000313|EMBL:PNJ56849.1};
RA Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT "High-resolution comparative analysis of great ape genomes.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPPYP00000000799.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; NDHI03003420; PNJ56849.1; -; Genomic_DNA.
DR RefSeq; XP_009240983.1; XM_009242708.1.
DR STRING; 9601.ENSPPYP00000000799; -.
DR Ensembl; ENSPPYT00000000830.2; ENSPPYP00000000799.1; ENSPPYG00000000690.2.
DR eggNOG; ENOG502S65W; Eukaryota.
DR GeneTree; ENSGT01050000244808; -.
DR HOGENOM; CLU_023383_6_1_1; -.
DR OrthoDB; 3026247at2759; -.
DR TreeFam; TF351107; -.
DR Proteomes; UP000001595; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00096; Ig; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 6.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR11481:SF109; FC RECEPTOR-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR11481; IMMUNOGLOBULIN FC RECEPTOR; 1.
DR Pfam; PF00047; ig; 2.
DR Pfam; PF13895; Ig_2; 2.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 6.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF48726; Immunoglobulin; 6.
DR PROSITE; PS50835; IG_LIKE; 6.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001595};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..742
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014574589"
FT TRANSMEM 576..598
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..94
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 99..183
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 193..271
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 285..376
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 384..471
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 477..564
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 608..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 699..718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..632
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 742 AA; 81809 MW; AE2729578685D1AD CRC64;
MLLWLLLLIL TPGREQSGVA PKAVLLLDPP WSTAFKGERV ALICRGISHS PAQGDTYWYR
NEKLLKIKYN KIQITESGNY QCKTRGSSLS DAVHVGFSPD WLILQASHPV FEGDNVILRC
QGKDDKNTHQ KVYYKDGKQL PNSYNLDNIT VNSVSRDNSK YHCTATCKRF YMINFKETSK
HLNIQVQELF LHPVLRASSS TPIEGSPMTL TCETQLSPQR PNIQLQFSFF RDSQTLGSGW
SRSPKLQIPA MWTEDSGSYW CEVETVTHSI KKRSLRSQIR VQRVPVSNVN LEIRPTGGQL
IEGENMVLIC SVAQGSGTVT FSWHKEGRVR SLGRKSQRSL LAELHVLTVK ESDAGKYYCA
ADNVHGPILS TWIRVTVRIP VSHPILTFRA PRAHAVVGDL LELHCESLRG SPPILYRFYH
EDVTLGNSSA PSGGGASFNL SLTAEHSGNY SCDADNGLGA QHSHGVSLRV TVPVSRPVLT
LRAPGAQAVV GDLLELHCES LRGSFPILYW FYHEDDTLGN SSAHSGGGAS FNLSLTTEHS
GNYSCEADNG LGAQHSKVVT LNVTGTSRSR TGLTTVGVTG LVLSILGLAA AAALLHYARA
RTKLEGLSAT GTSSHSPSEC QEASSSRFSR IDPQEPTHSK PLAPMELEPM YSNVNPGDSN
LIYSQIWSIQ HTKENSANCP TMHQEHEELT VLYSELKKTH PDDSAGEASS RHRAHENDEE
NYENILNLIK DKIQDFPCLC NT
//
