ID H2N7U3_PONAB Unreviewed; 398 AA.
AC H2N7U3; A0A2J8Y637; A0A2J8Y670;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=SMAP2 isoform 2 {ECO:0000313|EMBL:PNJ89743.1};
DE SubName: Full=Small ArfGAP2 {ECO:0000313|Ensembl:ENSPPYP00000001722.2};
GN Name=SMAP2 {ECO:0000313|Ensembl:ENSPPYP00000001722.2};
GN ORFNames=CR201_G0015554 {ECO:0000313|EMBL:PNJ89743.1};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000001722.2, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000001722.2, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PNJ89743.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Susie {ECO:0000313|EMBL:PNJ89743.1};
RA Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT "High-resolution comparative analysis of great ape genomes.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPPYP00000001722.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; NDHI03003278; PNJ89743.1; -; Genomic_DNA.
DR STRING; 9601.ENSPPYP00000024249; -.
DR Ensembl; ENSPPYT00000001778.2; ENSPPYP00000001722.2; ENSPPYG00000001490.3.
DR GeneTree; ENSGT00940000158387; -.
DR OrthoDB; 1022106at2759; -.
DR Proteomes; UP000001595; Chromosome 1.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR45705; FI20236P1; 1.
DR PANTHER; PTHR45705:SF4; STROMAL MEMBRANE-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000001595};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 1..107
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 131..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 188..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 398 AA; 43401 MW; 2FFA116957FC3050 CRC64;
MIFKGPRWAS WNIGVFICIR CAGIHRNLGV HISRVKSVNL DQWTQEQIQC MQEMGNGKAN
RLYEAYLPET FRRPQIDPAV EGFIRDKYEK KKYMDRSLDI NAFRKEKDDR WKRGSEPVPE
KKLEPVVFEK VKMPQKKEDP QLPRKSSPKS TAPVMDLLGL DAPVACSIAN SKTSNTLEKD
LDLLASVPSP SSGSRKVVGS MPTAGSAGSV PENLNLFPEP GSKSEEIGKK QLSKDSILSL
YGSQTPQMPT QAMFMAPAQM AYPTAYPSFP GVTPPNSIMG SMMPPPVGMV AQPGASGTVA
PMAMPAGYMG GMQASMMGVP NGMMTTQQAG YMAGMAAMPQ TVYGVQPAQQ LQWNLTQMTQ
QMAGMNFYGA NGMMNYGQSM SGGNGQAANQ TLSPQMWK
//
