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Database: UniProt
Entry: H2NDQ5_PONAB
LinkDB: H2NDQ5_PONAB
Original site: H2NDQ5_PONAB 
ID   H2NDQ5_PONAB            Unreviewed;       265 AA.
AC   H2NDQ5; A0A2J8WG26;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   16-OCT-2019, entry version 49.
DE   SubName: Full=ELF5 isoform 6 {ECO:0000313|EMBL:PNJ68704.1};
GN   Name=ELF5 {ECO:0000313|Ensembl:ENSPPYP00000003862};
GN   ORFNames=CR201_G0011096 {ECO:0000313|EMBL:PNJ68704.1};
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Pongo.
OX   NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000003862, ECO:0000313|Proteomes:UP000001595};
RN   [1] {ECO:0000313|Ensembl:ENSPPYP00000003862, ECO:0000313|Proteomes:UP000001595}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Wilson R.K., Mardis E.;
RT   "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPPYP00000003862}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [3] {ECO:0000313|EMBL:PNJ68704.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Susie {ECO:0000313|EMBL:PNJ68704.1};
RA   Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R.,
RA   Chaisson M., Hoppe E., Hill C., Pang A., Hillier L., Baker C.,
RA   Armstrong J., Shendure J., Paten B., Wilson R., Chao H., Schneider V.,
RA   Ventura M., Kronenberg Z., Murali S., Gordon D., Cantsilieris S.,
RA   Munson K., Nelson B., Raja A., Underwood J., Diekhans M., Fiddes I.,
RA   Haussler D., Eichler E.;
RT   "High-resolution comparative analysis of great ape genomes.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family.
CC       {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594391}.
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DR   EMBL; ABGA01148240; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABGA01148241; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABGA01148242; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABGA01148243; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; NDHI03003391; PNJ68704.1; -; Genomic_DNA.
DR   RefSeq; XP_002821939.1; XM_002821893.1.
DR   STRING; 9601.ENSPPYP00000003862; -.
DR   Ensembl; ENSPPYT00000004010; ENSPPYP00000003862; ENSPPYG00000003363.
DR   GeneID; 100458821; -.
DR   CTD; 2001; -.
DR   eggNOG; KOG3804; Eukaryota.
DR   eggNOG; ENOG4111K4J; LUCA.
DR   GeneTree; ENSGT00940000160980; -.
DR   InParanoid; H2NDQ5; -.
DR   OMA; FNDTEET; -.
DR   OrthoDB; 837296at2759; -.
DR   TreeFam; TF318679; -.
DR   Proteomes; UP000001595; Chromosome 11.
DR   GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR   GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0001712; P:ectodermal cell fate commitment; IEA:Ensembl.
DR   GO; GO:0060644; P:mammary gland epithelial cell differentiation; IEA:Ensembl.
DR   GO; GO:0045596; P:negative regulation of cell differentiation; IEA:Ensembl.
DR   GO; GO:0035019; P:somatic stem cell population maintenance; IEA:Ensembl.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR033069; Elf5.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11849:SF15; PTHR11849:SF15; 1.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001595};
KW   DNA-binding {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001595}.
FT   DOMAIN       43    129       PNT. {ECO:0000259|PROSITE:PS51433}.
FT   DOMAIN      173    254       ETS. {ECO:0000259|PROSITE:PS50061}.
SQ   SEQUENCE   265 AA;  31286 MW;  1A7BE71080C1B0E6 CRC64;
     MPSLPHSHRV MLDSVTHSTF LPNASFCDPL MSWTDLFSNE EYYPAFEHQT ACDSYWTSVH
     PEYWTKRHVW EWLQFCCDQY KLDTNCISFC HFNISGLQLC SMTQEEFVEA AGLCGEYLYF
     ILQNIRTQGY SFFNDAEESK ATIKDYADSN CLKTSGIKSQ DCHSHSRTSL QSSHLWEFVR
     DLLLSPEENC GILEWEDREQ GIFRVVKSEA LAKMWGQRKK NDRMTYEKLS RALRYYYKTG
     ILERVDRRLV YKFGKNAHGW QEDKL
//
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