ID H2NF93_PONAB Unreviewed; 375 AA.
AC H2NF93; A0A2J8X261;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Layilin {ECO:0000313|Ensembl:ENSPPYP00000004423.3};
GN Name=LAYN {ECO:0000313|Ensembl:ENSPPYP00000004423.3};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000004423.3, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000004423.3, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPPYP00000004423.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H2NF93; -.
DR STRING; 9601.ENSPPYP00000004423; -.
DR Ensembl; ENSPPYT00000004598.3; ENSPPYP00000004423.3; ENSPPYG00000003862.3.
DR eggNOG; KOG4297; Eukaryota.
DR GeneTree; ENSGT00390000001844; -.
DR HOGENOM; CLU_045492_1_1_1; -.
DR InParanoid; H2NF93; -.
DR OMA; ICKYSNE; -.
DR OrthoDB; 4625794at2759; -.
DR TreeFam; TF330715; -.
DR Proteomes; UP000001595; Chromosome 11.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd03595; CLECT_chondrolectin_like; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR016187; CTDL_fold.
DR PANTHER; PTHR14789; CHONDROLECTIN VARIANT CHODLFDELTAE; 1.
DR PANTHER; PTHR14789:SF2; LAYILIN; 1.
DR Pfam; PF00059; Lectin_C; 1.
DR SMART; SM00034; CLECT; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001595};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..375
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5035201296"
FT TRANSMEM 225..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..177
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT REGION 185..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 375 AA; 42219 MW; FAF56CE931DF8411 CRC64;
MRPGTALQAV VLAVLLVGLR AATGRLLSGQ PVCRGGTQRP CYKVIYFHDT SRRLNFEEAK
EACRRDGGQL VSIESEDEQK LIEKFIENLL PSDGDFWIGL RRREEKQSNS TACQDLYAWT
DGSISQFRNW YVDEPSCGSE VCVVMYHQPS APAGIGGPYM FQWNDDRCNM KNNFVCKYSD
EKPAVPSREA EGEETEPTTP VLPEETQEED AKKTFKESRE AALNLAYTLI PSIPLLLLLV
VTTVVCWVWI CRRRKREQPD PSTKKQHTIW PSPHQGNSPD LEVYNVIRKQ SEADLAETRP
DLKNISFRVC SGEATPDDMS CDYDNMAVNP SESGFVTLAT GSHVSHPTEV NPEIPFLYSF
PSLACENANR LCDLR
//
