ID H2NFX7_PONAB Unreviewed; 438 AA.
AC H2NFX7;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000004662.2};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000004662.2, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000004662.2, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPPYP00000004662.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR AlphaFoldDB; H2NFX7; -.
DR Ensembl; ENSPPYT00000004847.2; ENSPPYP00000004662.2; ENSPPYG00000036793.1.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00940000163213; -.
DR HOGENOM; CLU_013137_7_2_1; -.
DR InParanoid; H2NFX7; -.
DR OMA; VICEKHQ; -.
DR TreeFam; TF338674; -.
DR Proteomes; UP000001595; Chromosome 11.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16603; RING-HC_TRIM43-like_C-IV; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF632; E3 UBIQUITIN-PROTEIN LIGASE TRIM48; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001595};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 15..55
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 255..438
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 438 AA; 51233 MW; 2D99A31249429E3B CRC64;
MNSGISQVFR RELTCPICMN CFIDPVIIDC GHSFCRPCFY LNWQDIPILT QCFECIKTTQ
QRNLKTNIRL KKMVSLARKA SLWLFLSSEE QMCGTHRETK KMFSLEHRYH RHRPVEWAGE
EQREKLLTKM QSLWEKACEN QRNLNVETTR ISHWKDYVNV RLEAIRAEYQ KMPAFHHEEE
KHNLEMLKKK GKDIFHQLHL SKAKMAHRRE ILRGTYEELM KMCHKPDVEL LQAFGDILYR
TESVLLHMRQ PLNLELRAGP VTGLRDRLNQ FRVDITLHHN EANSHIFRCG DLRSICIGCD
RQNAPHITAT PTSFLAWGAQ NFTSGKYYWE VHVGDSWNWA FGVCNKYWKG KNQNGNIYGE
EGLFSLECVK NDIQCSLFTT SPMTLQYVPR PTSHVGLFLD CEARTVSFVD VNQSSPIYTI
PNCSFSPPLR PIFSCIHL
//
