GenomeNet

Database: UniProt
Entry: H2NIP8_PONAB
LinkDB: H2NIP8_PONAB
Original site: H2NIP8_PONAB 
ID   H2NIP8_PONAB            Unreviewed;       651 AA.
AC   H2NIP8;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   08-MAY-2019, entry version 41.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000005670};
GN   Name=LOC100436554 {ECO:0000313|Ensembl:ENSPPYP00000005670};
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Pongo.
OX   NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000005670, ECO:0000313|Proteomes:UP000001595};
RN   [1] {ECO:0000313|Ensembl:ENSPPYP00000005670, ECO:0000313|Proteomes:UP000001595}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Wilson R.K., Mardis E.;
RT   "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPPYP00000005670}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; ABGA01147490; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABGA01235085; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABGA01235086; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSPPYT00000005887; ENSPPYP00000005670; ENSPPYG00000004969.
DR   eggNOG; KOG3607; Eukaryota.
DR   eggNOG; ENOG410XX2M; LUCA.
DR   GeneTree; ENSGT00940000161891; -.
DR   Proteomes; UP000001595; Chromosome 12.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   CDD; cd04269; ZnMc_adamalysin_II_like; 1.
DR   Gene3D; 3.40.390.10; -; 1.
DR   Gene3D; 4.10.70.10; -; 1.
DR   InterPro; IPR006586; ADAM_Cys-rich.
DR   InterPro; IPR018358; Disintegrin_CS.
DR   InterPro; IPR001762; Disintegrin_dom.
DR   InterPro; IPR036436; Disintegrin_dom_sf.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   InterPro; IPR001590; Peptidase_M12B.
DR   InterPro; IPR002870; Peptidase_M12B_N.
DR   InterPro; IPR034027; Reprolysin_adamalysin.
DR   Pfam; PF08516; ADAM_CR; 1.
DR   Pfam; PF00200; Disintegrin; 1.
DR   Pfam; PF01562; Pep_M12B_propep; 1.
DR   Pfam; PF01421; Reprolysin; 1.
DR   PRINTS; PR00289; DISINTEGRIN.
DR   SMART; SM00608; ACR; 1.
DR   SMART; SM00050; DISIN; 1.
DR   SUPFAM; SSF57552; SSF57552; 1.
DR   PROSITE; PS50215; ADAM_MEPRO; 1.
DR   PROSITE; PS00427; DISINTEGRIN_1; 1.
DR   PROSITE; PS50214; DISINTEGRIN_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001595};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00068,
KW   ECO:0000256|SAAS:SAAS00877335}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001595};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    633    650       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      148    342       Peptidase M12B. {ECO:0000259|PROSITE:
FT                                PS50215}.
FT   DOMAIN      351    435       Disintegrin. {ECO:0000259|PROSITE:
FT                                PS50214}.
FT   DISULFID    407    427       {ECO:0000256|PROSITE-ProRule:PRU00068}.
SQ   SEQUENCE   651 AA;  72398 MW;  5EE28977DCEF18DA CRC64;
     YSFYEIIIPK RLTVQGGDSP VEGLSYLLFM QGQKHLVHLK VKRSHFVNNF PVYSYHNGIL
     GQEVPFISHD CHYEGYIEGV SGSFVSVNTC AGLRGILIKE EKSYSIEPMD SSRRFEHVLY
     TMAHQAWQQG SRKLHDLQAL SYLWSHKKYV EMFVVVNNQR FQMWGSNVNE TVQRVVDVIA
     LANSFTRGIN TRVVLAGMEI WTEGDLIDVT VDLQITLRNF NHWRQEMLFH RAKHDVAHMI
     VGHHPGQKMG QAFLSGACSS GFAAAVESFH HEDVLLFAAL MVHELGHNLG IQHDHSACFC
     KDKHFCLMHE NITKESGFSN CSSDYFYQFL REHKGACLFN KPWPRVRKRR DSACGNGVVE
     DTEQCDCGSL CQRHPCCDEN CILKAKAECS DGPCCHKCKF QRKGYPCRPS SRSCDLPEFC
     NGTSALCPDN RHKQDGSKCH KIYECLKGHC MDPNNQCLEL FGYGAKSASQ ECYNSMNSKG
     DRFGNCGIST SPRSQYVRCS DGNIFCGKLI CSGIIGLPKI NLQHTVIQVP QGDGSCWSMD
     AYTSTDIPDE GDVHNGTYCA PNKVCLNSAC TDKTPVIFAC NPEKTCNGKG VCNDLGHCHC
     NEGHAPPDCV TAGGGGSVDS GPPGKPSGTT SDMMILSFII LFIILLLSTI I
//
DBGET integrated database retrieval system