ID H2NJD7_PONAB Unreviewed; 291 AA.
AC H2NJD7; A0A2J8RYW1;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Gamma-sarcoglycan {ECO:0000256|ARBA:ARBA00020453};
GN Name=SGCG {ECO:0000313|Ensembl:ENSPPYP00000005927.3};
GN ORFNames=CR201_G0047707 {ECO:0000313|EMBL:PNJ13705.1};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000005927.3, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000005927.3, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PNJ13705.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Susie {ECO:0000313|EMBL:PNJ13705.1};
RA Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT "High-resolution comparative analysis of great ape genomes.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPPYP00000005927.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Component of the sarcoglycan complex, a subcomplex of the
CC dystrophin-glycoprotein complex which forms a link between the F-actin
CC cytoskeleton and the extracellular matrix.
CC {ECO:0000256|ARBA:ARBA00002860}.
CC -!- SUBCELLULAR LOCATION: Cell membrane, sarcolemma
CC {ECO:0000256|ARBA:ARBA00004274}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004274}.
CC -!- SIMILARITY: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
CC {ECO:0000256|ARBA:ARBA00007574}.
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DR EMBL; NDHI03003634; PNJ13705.1; -; Genomic_DNA.
DR STRING; 9601.ENSPPYP00000005927; -.
DR Ensembl; ENSPPYT00000006161.3; ENSPPYP00000005927.3; ENSPPYG00000005204.3.
DR eggNOG; KOG3950; Eukaryota.
DR GeneTree; ENSGT00940000159187; -.
DR HOGENOM; CLU_043450_0_0_1; -.
DR OMA; CACFNGK; -.
DR TreeFam; TF313538; -.
DR Proteomes; UP000001595; Chromosome 13.
DR GO; GO:0016012; C:sarcoglycan complex; IEA:InterPro.
DR GO; GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
DR InterPro; IPR006875; Sarcoglycan.
DR InterPro; IPR039972; Sarcoglycan_gamma/delta/zeta.
DR PANTHER; PTHR12939:SF4; GAMMA-SARCOGLYCAN; 1.
DR PANTHER; PTHR12939; SARCOGLYCAN; 1.
DR Pfam; PF04790; Sarcoglycan_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001595};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 291 AA; 32344 MW; F153AA5C827BA115 CRC64;
MVREQYTTAT EGTRIERPEN QYVYKIGIYG WRKRCLYLFV LLLLIILVVN LALTIWILKV
MWFSPAGMGH LRVTNDGLRL EGESEFLLPL YAKEIHSRVD SSLLLQSTQN VTVNAHNSEG
EVTGRLKVGP KMVEVQSQQF QINSNDGKPL FTVDEKEVVV GTDKLRVTGP EGALFEHSVE
TPLVRADPFE DLRLESPTRS LSMDAPRGVH IQAHAGKIEA LSQMDILFQS SDGMLVLDAE
TVCLPKLVQG TWGPSGSSQS LYEICVCPDG KLYLSVAGVS TTCQEHSHIC L
//
