ID H2NK89_PONAB Unreviewed; 264 AA.
AC H2NK89; A0A2J8X8B1; A0A6D2Y1N3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=METTL21C isoform 1 {ECO:0000313|EMBL:PNJ78265.1};
DE SubName: Full=Methyltransferase 21C, AARS1 lysine {ECO:0000313|Ensembl:ENSPPYP00000006247.1};
GN Name=METTL21C {ECO:0000313|Ensembl:ENSPPYP00000006247.1};
GN ORFNames=CR201_G0004244 {ECO:0000313|EMBL:PNJ78265.1};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000006247.1, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000006247.1, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PNJ78265.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Susie {ECO:0000313|EMBL:PNJ78265.1};
RA Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT "High-resolution comparative analysis of great ape genomes.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPPYP00000006247.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; NDHI03003370; PNJ78265.1; -; Genomic_DNA.
DR RefSeq; XP_002824455.1; XM_002824409.3.
DR STRING; 9601.ENSPPYP00000006247; -.
DR Ensembl; ENSPPYT00000006493.2; ENSPPYP00000006247.1; ENSPPYG00000005479.2.
DR GeneID; 100433072; -.
DR KEGG; pon:100433072; -.
DR CTD; 196541; -.
DR eggNOG; KOG2793; Eukaryota.
DR GeneTree; ENSGT00940000156596; -.
DR HOGENOM; CLU_055721_0_0_1; -.
DR OMA; FDKEHYC; -.
DR OrthoDB; 2902182at2759; -.
DR TreeFam; TF354267; -.
DR Proteomes; UP000001595; Chromosome 13.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR GO; GO:0031072; F:heat shock protein binding; IEA:Ensembl.
DR GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IEA:Ensembl.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR019410; Methyltransf_16.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR14614; HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN; 1.
DR PANTHER; PTHR14614:SF13; PROTEIN-LYSINE METHYLTRANSFERASE METTL21C; 1.
DR Pfam; PF10294; Methyltransf_16; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000001595};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 264 AA; 29546 MW; A8133C15626FB2A9 CRC64;
MDVCLSSAQQ PGRRGEGLSS PGVWLEAEKK GAPQKDSTGG VLEESNKIEP SLHSLQKFVP
TDYASYTQEH YRFAGKEIVI QESIESYGAV VWPGATALCQ YLEEHAEELN FQDAKILEIG
AGPGLVSIVA SILGAQVTAT DLPDVLGNLQ YNLLKNTLQC TAHLPEVKEL VWGEDLDKNF
PKSAFYYDYV LASDVVYHHY FLDKLLATMV YLSQPGTVLL WANKFRFSTD YEFLDKFKQV
FDTTLLAEYP ESSVKLFKGI LKWD
//
