ID H2NPY4_PONAB Unreviewed; 549 AA.
AC H2NPY4; A0A2J8S7N4; A0A6D2XMW1;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=TIGD7 isoform 4 {ECO:0000313|EMBL:PNJ16776.1};
DE SubName: Full=Tigger transposable element derived 7 {ECO:0000313|Ensembl:ENSPPYP00000007961.1};
GN Name=TIGD7 {ECO:0000313|Ensembl:ENSPPYP00000007961.1};
GN ORFNames=CR201_G0045593 {ECO:0000313|EMBL:PNJ16776.1};
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000007961.1, ECO:0000313|Proteomes:UP000001595};
RN [1] {ECO:0000313|Ensembl:ENSPPYP00000007961.1, ECO:0000313|Proteomes:UP000001595}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Wilson R.K., Mardis E.;
RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PNJ16776.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Susie {ECO:0000313|EMBL:PNJ16776.1};
RA Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT "High-resolution comparative analysis of great ape genomes.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPPYP00000007961.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00320}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NDHI03003602; PNJ16776.1; -; Genomic_DNA.
DR RefSeq; XP_009248680.1; XM_009250405.1.
DR Ensembl; ENSPPYT00000008292.2; ENSPPYP00000007961.1; ENSPPYG00000007039.2.
DR GeneID; 103892622; -.
DR KEGG; pon:103892622; -.
DR CTD; 91151; -.
DR eggNOG; KOG3105; Eukaryota.
DR GeneTree; ENSGT00940000163295; -.
DR HOGENOM; CLU_018294_1_1_1; -.
DR OMA; WFTRESF; -.
DR OrthoDB; 2967227at2759; -.
DR TreeFam; TF101131; -.
DR Proteomes; UP000001595; Chromosome 16.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR004875; DDE_SF_endonuclease_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR InterPro; IPR007889; HTH_Psq.
DR PANTHER; PTHR19303:SF17; TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 7; 1.
DR PANTHER; PTHR19303; TRANSPOSON; 1.
DR Pfam; PF04218; CENP-B_N; 1.
DR Pfam; PF03184; DDE_1; 1.
DR Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR SMART; SM00674; CENPB; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51253; HTH_CENPB; 1.
DR PROSITE; PS50960; HTH_PSQ; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Reference proteome {ECO:0000313|Proteomes:UP000001595}.
FT DOMAIN 1..52
FT /note="HTH psq-type"
FT /evidence="ECO:0000259|PROSITE:PS50960"
FT DOMAIN 68..139
FT /note="HTH CENPB-type"
FT /evidence="ECO:0000259|PROSITE:PS51253"
FT DNA_BIND 28..48
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00320"
FT REGION 527..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 549 AA; 63159 MW; 3E6B201BC0FBB148 CRC64;
MNKRGKYTTL NLEEKMKVLS RIEAGRSLKS VMDEFGISKS TFYDIKKNKK LILDFVLKQD
MPLVGAEKRK RTTGAKYGDV DDAVYMWYQQ KRSAGVPVRG VELQAAAERF ARCFGRIDFK
ASTGWLFRFR NRHAIGNRKG CGEQVLSSVS ENVEPFRQKL STIIKEEKLC LAQLYSGDET
DLFWKSMPEN SQASRKDICL PGKKINKERL SALLCANADG THKLKSIIIG KSKLPKSVKE
DTSTLPVIYK PSKDVWFTRE LFSEWFFQNF VPEVRHFQLN VLRFHEEDVR ALLLLDSCPA
HPSSESLTSE DGRIKCMFFP HNTSALIQPM NQGVILSCKR LYRWKQLEES LVIFEESDDE
QEKGDKGVSK IKIYNIKSAI FNWAKSWDEV KQITIANAWE NLLYKKEPEY DFQGLEDGDY
REILEKCGEL ETKLDDDRVW LNGDEEKGCL LKTKGGITKE VVQKGGEAEK QTAEFKLSAV
RQSLDYLLDF VDATPEFRRF HFTLKEMQQE IVKKQFQSKI HSRIGSFLKP RPHNIKDSFS
GPSTSGSNH
//
