ID   H2NQL1_PONAB            Unreviewed;       945 AA.
AC   H2NQL1; A0A2J8TK50;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   25-MAY-2022, sequence version 2.
DT   27-MAR-2024, entry version 74.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   Name=TAOK2 {ECO:0000313|Ensembl:ENSPPYP00000008196.3};
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000008196.3, ECO:0000313|Proteomes:UP000001595};
RN   [1] {ECO:0000313|Ensembl:ENSPPYP00000008196.3, ECO:0000313|Proteomes:UP000001595}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Wilson R.K., Mardis E.;
RT   "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPPYP00000008196.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; H2NQL1; -.
DR   STRING; 9601.ENSPPYP00000008196; -.
DR   Ensembl; ENSPPYT00000008533.3; ENSPPYP00000008196.3; ENSPPYG00000007250.3.
DR   eggNOG; KOG0577; Eukaryota.
DR   GeneTree; ENSGT00940000159991; -.
DR   HOGENOM; CLU_000288_2_2_1; -.
DR   InParanoid; H2NQL1; -.
DR   OMA; WTDVFRH; -.
DR   OrthoDB; 2879376at2759; -.
DR   TreeFam; TF351444; -.
DR   Proteomes; UP000001595; Chromosome 16.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR47167; SERINE/THREONINE-PROTEIN KINASE TAO1-LIKE PROTEIN; 1.
DR   PANTHER; PTHR47167:SF6; SERINE_THREONINE-PROTEIN KINASE TAO2; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001595};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          1..177
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          214..353
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          827..945
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          388..415
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        240..269
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        270..291
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        848..881
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        927..945
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   945 AA;  107309 MW;  A07A3F8817D6C6A3 CRC64;
     MEYCLGSASD LLEVHKKPLQ EVEIAAVTHG ALQGLAYLHS HNMIHRDVKA GNILLSEPGL
     VKLGDFGSAS IMAPANSFVG TPYWMAPEVI LAMDEGQYDG KVDVWSLGIT CIELAERKPP
     LFNMNAMSAL YHIAQNESPV LQSGHWSEYF RNFVDSCLQK IPQDRPTSEV LLKHRFVLRE
     RPPTVIMDLI QRTKDAVREL DNLQYRKMKK ILFQEAPNGP GAEAPEEEEE AEPYMHRAGT
     LTSLESSHSV PSMSISASSQ SSSVNSLADA SDNEEEEEEE EEEEEEEEGP EAREMAMMQE
     GEHTVTSHSS IIHRLPGSDN LYDDPYQPEI TPSPLQPPAA PAPTSTTSSA RRRAYCRNRD
     HFATIRTASL VSRQIQEHEQ DSALREQLSG YKRMRRQHQK QLLALESRLR GEREEHSARL
     QRELEAQRAG FGAEAEKLAR RHQAIGEKEA RAAQAEERKF QQHILGQQKK ELAALLEAQK
     RTYKLRKEQL KEELQENPST PKREKAEWLL RQKEQLQQCQ AEEEAGLLRR QRQYFELQCR
     QYKRKMLLAR HSLDQDLLRE DLNKKQTQKD LECALLLRQH EATRELELRQ LQAVQRTRAE
     LTRLQHQTEL GNQLEYNKRR EQELRQKHAA QVRQQPKSLK SKELQIKKQF QETCKIQTRQ
     YKALRAHLLE TTPKAQHKSL LKRLKEEQTR KLAILAEQYD QSISEMLSSQ ALRLDETQEA
     EFQALRQQLQ QELELLNAYQ SKIKIRTESQ HERELRELEQ RVALRRALLE QRVEEELLAL
     QTGRSERIRS LLERQAREIE AFDAESMRLG FSSMALGGIP AEAAAQGYPA PPPAPAWPSR
     PVPRSGAHWS HGPPPPGMPP PAWRQPSLLA PPGPPNWLGP PTQSGTPRGG ALLLLRNSPQ
     PLRRAASGGS GSENVGPPAA AVPGPLSRST SVASHILNGS SHFYS
//