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Database: UniProt
Entry: H2NTD2_PONAB
LinkDB: H2NTD2_PONAB
Original site: H2NTD2_PONAB 
ID   H2NTD2_PONAB            Unreviewed;       902 AA.
AC   H2NTD2;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   03-JUL-2019, entry version 39.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000009201};
GN   Name=SLFN11 {ECO:0000313|Ensembl:ENSPPYP00000009201};
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Pongo.
OX   NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000009201, ECO:0000313|Proteomes:UP000001595};
RN   [1] {ECO:0000313|Ensembl:ENSPPYP00000009201, ECO:0000313|Proteomes:UP000001595}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Wilson R.K., Mardis E.;
RT   "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPPYP00000009201}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; ABGA01157185; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9601.ENSPPYP00000009201; -.
DR   Ensembl; ENSPPYT00000009572; ENSPPYP00000009201; ENSPPYG00000008183.
DR   eggNOG; ENOG410IJEW; Eukaryota.
DR   eggNOG; ENOG410Z5MV; LUCA.
DR   GeneTree; ENSGT00410000025651; -.
DR   InParanoid; H2NTD2; -.
DR   OMA; QHLYIFP; -.
DR   TreeFam; TF337168; -.
DR   Proteomes; UP000001595; Chromosome 17.
DR   GO; GO:0016235; C:aggresome; IEA:Ensembl.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0090734; C:site of DNA damage; IEA:Ensembl.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATPase activity; IEA:Ensembl.
DR   GO; GO:0000049; F:tRNA binding; IEA:Ensembl.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:Ensembl.
DR   GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR   GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0010942; P:positive regulation of cell death; IEA:Ensembl.
DR   GO; GO:0043111; P:replication fork arrest; IEA:Ensembl.
DR   Gene3D; 3.30.950.30; -; 1.
DR   InterPro; IPR018647; DUF2075.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR029684; Schlafen.
DR   InterPro; IPR007421; Schlafen_AlbA_2_dom.
DR   InterPro; IPR038461; Schlafen_AlbA_2_dom_sf.
DR   PANTHER; PTHR12155; PTHR12155; 1.
DR   Pfam; PF04326; AlbA_2; 1.
DR   Pfam; PF09848; DUF2075; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001595};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001595}.
FT   DOMAIN      210    279       AlbA_2. {ECO:0000259|Pfam:PF04326}.
FT   DOMAIN      596    677       DUF2075. {ECO:0000259|Pfam:PF09848}.
SQ   SEQUENCE   902 AA;  102759 MW;  BB98607E0FAD519A CRC64;
     MEANQCPVVV EPSYPDLVIN VGEVTLGEEN RKKLQKIQRD HEKERVMQAA CALLNSGGGV
     IRMAKKVEHP VEMGLDLEQS LRELIQSSDL QAFFETKQQG RRFYIFVKSW SSGPFPEDGS
     VKPRLCSLSS SLYRRSETSV RSMDSREAFC FLKAKKRKAK ILEEGPFHKI HKGIHQELPN
     SDPADPNSDP ADPIFQKDYL EYGEILPFPE SQLVEFKQFS TKHIQEYVKK IIPEYVPAFA
     NTGGGYLFIG VDDKSRKVLG CAKENVDPDS LRRKIEKAIY KLPCVHFCQP QRPITFTLKI
     VDVLKRGELY GYACMIRVKP FCCAVFSEAP NSWIVEDKYV CSLTTEKWVG MMTDTDPDLL
     QLSKDFECQL SLSSGPPLSR PVYSKKGLEH KKELQQLLFS VPPGYLRYTP ESLWRDLTSE
     HEGLGELINK QMRPFFRGIL IFSRSWAVDL NLQEKPGVIC DALLIAQNST PILYTILREQ
     DAEGQDYCTR TAFTLKQKLV NMGGYTGKVC VKAKVLCLRP ESSAEALEAS VSPMDYPASY
     SLAGTEHMEA LLQSLVIVLL GFRSLLSDQL GCEVLNLLTA KQYEILSRSL RKNRELFVHG
     LPGSGKTIIA INIMEKIRNV FHCEEKRILY VCENQPLRNF ISHKNICQAE TRKTFLRENF
     EHIQHIVIDE AQNFRTEDGD WYGKAKTITR RAKDGPGILW IFLDYFQTSH LDCSGLPPLS
     DQYSIEELTR IVRNADPIAK YLQKEMQVIR NNPSFNIPTG CLEVLLEAEW SQGVQGTLQI
     KKHLTVEQIM TYVADTCRRF FERGYSPKDV AVLVSTAKEV EHYKYELLKA MRKKRVVQLS
     DACDMLGDHI VLDSVRRFSG LERNIVFGIH PRTADPAILP NILICLASRA KQHLYIFPWG
     GH
//
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